Pretreatment thrombocytosis : A prognostic marker for oral squamous cell carcinoma?
Summary of "Pretreatment thrombocytosis : A prognostic marker for oral squamous cell carcinoma?"
PURPOSE:
Thrombocytosis associated with poorer prognoses seems to be a frequent preoperative finding in different kind of cancers. The aim of the present study was to evaluate whether thrombocytosis can be used as a prognostic marker for oral squamous cell carcinoma (SCC).
METHODS:
Altogether, 288 patients with oral SCC were considered, as well as all platelet counts between 1 and 5 days prior to surgical treatment, recurrence rate, and lymph node metastasis. The minimum follow-up time was 12 months.
RESULTS:
The mean preoperative thrombocyte score of the patients who received surgery was 259.55 ± 83.8 Tsd/μl; 273 out of 288 patients were in the normal thrombocyte range, and 12 had a thrombocytosis. From 51 patients with recurrence, three were in the thrombocytosis group, and 45 patients with recurrence were in the normal thrombocyte range.
CONCLUSION:
The present results do not confirm that thrombocytosis can be seen as marker for poor tumor prognosis.
Affiliation
Department of Craniomaxillofacial and Oral Surgery, University Hospital Zurich, Frauenklinikstr. 24, 8091, Zurich, Switzerland.
Journal Details
This article was published in the following journal.
Name: Oral and maxillofacial surgery
ISSN: 1865-1569
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22108700
- DOI: http://dx.doi.org/10.1007/s10006-011-0305-6
Medical and Biotech [MESH] Definitions
Carcinoma, Squamous Cell
A carcinoma derived from stratified squamous epithelium. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
Carcinoma, Non-small-cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.
Carcinoma, Adenosquamous
A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.
Granular Cell Tumor
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.
Carcinoma, Basosquamous
A skin carcinoma that histologically exhibits both basal and squamous elements. (From Dorland, 27th ed)
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