Preoperative prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in patients undergoing intranasal surgery.
Summary of "Preoperative prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in patients undergoing intranasal surgery."
Background: The goal of this study was to determine the rates of carriage of methicillin-resistant Staphylococcus aureus among patients undergoing intranasal surgery. Material/Methods: One hundred and sixty five patients undergoing inpatient and outpatient rhinologic surgery over a six-month period were enrolled in the study. Patients completed a short questionnaire prior to surgery. Culture swabs of the anterior nares and nasal vestibule were sent to the microbiology lab for evaluation for methicillin-resistant Staphylococcus aureus. Cultures were grown on a MRSA-specific agar plate and were considered final after 48 hours of incubation. The primary endpoint was a positive MRSA culture. Results: Of the one hundred fifty seven patients with nasal cultures taken, two had positive cultures for methicillin-resistant Staphylococcus aureus. Of those with positive cultures, both had a history of prior infection with methicillin-resistant Staphylococcus aureus. Conclusions: While antibiotic usage among the study group is far higher than the national average, the rates of nasal carriage of methicillin-resistant Staphylococcus aureus mirrors that described in other studies for the general population. The authors conclude that methicillin-resistant Staphylococcus aureus does not represent a significant source of infection among those undergoing intranasal surgery.
Affiliation
Department of Otolaryngology, Thomas Jefferson University Hospital, Philadelphia, PA, U.S.A.
Journal Details
This article was published in the following journal.
Name: Medical science monitor : international medical journal of experimental and clinical research
ISSN: 1643-3750
Pages: CR365-368
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20671612
- DOI: http://dx.doi.org/
Medical and Biotech [MESH] Definitions
Methicillin-resistant Staphylococcus Aureus
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
Staphylococcus Hominis
A species of STAPHYLOCOCCUS similar to STAPHYLOCOCCUS HAEMOLYTICUS, but containing different esterases. The subspecies Staphylococcus hominis novobiosepticus is highly virulent and novobiocin resistant.
Lysostaphin
A 25-kDa peptidase produced by Staphylococcus simulans which cleaves a glycine-glcyine bond unique to an inter-peptide cross-bridge of the STAPHYLOCOCCUS AUREUS cell wall. EC 3.4.24.75.
Pneumonia, Staphylococcal
Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.
Methicillin
One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
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