Diabetes mellitus, periapical inflammation and endodontic treatment outcome.
Summary of "Diabetes mellitus, periapical inflammation and endodontic treatment outcome."
The possible connection between chronic oral inflammatory processes, such as apical periodontitis and periodontal disease (PD), and systemic health is one of the most interesting aspects faced by the medical and dental scientific community. Chronic apical periodontitis shares important characteristics with
PD:
1) both are chronic infections of the oral cavity, 2) the Gram-negative anaerobic microbiota found in both diseases is comparable, and 3) in both infectious processes increased local levels of inflammatory mediators may have an impact on systemic levels. One of the systemic disorders linked to PD is diabetes mellitus (DM); is therefore plausible to assume that chronic apical periodontitis and endodontic treatment are also associated with DM. The status of knowledge regarding the relationship between DM and endodontics is reviewed. Upon review, we conclude that there are data in the literature that associate DM with a higher prevalence of periapical lesions, greater size of the osteolityc lesions, greater likelihood of asymptomatic infections and worse prognosis for root filled teeth. The results of some studies suggest that periapical disease may contribute to diabetic metabolic dyscontrol.
Affiliation
Dpto. Estomatología, Universidad de Sevilla, C/ Avicena s/n, 41009 Sevilla (SPAIN), segurajj@us.es.
Journal Details
This article was published in the following journal.
Name: Medicina oral, patologia oral y cirugia bucal
ISSN: 1698-6946
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22143698
- DOI: http://dx.doi.org/
Medical and Biotech [MESH] Definitions
Periapical Granuloma
Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.
Periapical Periodontitis
Inflammation of the PERIAPICAL TISSUE. It includes general, unspecified, or acute nonsuppurative inflammation. Chronic nonsuppurative inflammation is PERIAPICAL GRANULOMA. Suppurative inflammation is PERIAPICAL ABSCESS.
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Diabetes Mellitus, Experimental
Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Polyuria
Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).
PubMed Articles
Diabetes mellitus and hypertension are independent risk factors for endodontic failures.
Is endodontic treatment performed under general anaesthesia technically acceptable?
OBJECTIVES: Undertaking endodontic treatment under general anaesthesia (GA) is often described as difficult and hazardous, but no study reports on safe and efficacious conditions...
Abstract Objectives: This study investigated the long-term survival and the prognostic factors of endodontic treatments performed in a dental teaching hospital. The aim was to calculate the probabilit...
PURPOSE:: Diabetes mellitus is a prevalent medical disorder. It is often accompanied with systemic adverse sequelae, such as wound healing alterations, which may affect osseointegration of dental impl...
Pulp canal obliteration: an endodontic diagnosis and treatment challenge.
McCabe PS, Dummer PMH. Pulp canal obliteration: an endodontic diagnosis and treatment challenge. International Endodontic Journal. ABSTRACT: Aim To review the literature on pulp chamber and root ca...
Clinical Trials
Periodontal and Periapical Inflammation and Pregnancy
This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study. Recent animal studies we co...
Safety and Efficacy of the Apexum Ablator
The study is designed to test the hypothesis that there is a difference in healing kinetics and healing rate between teeth treated by conventional endodontic procedure alone and those in w...
Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery
The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions. People who have a higher body mass i...
Aliskiren is a novel renin inhibitor approved for the treatment of hypertension. The effect of aliskiren on arterial stiffness, inflammation and oxidative stress has not been fully investi...
The purpose of this study is to determine whether ruboxistaurin can reduce blood vessel inflammation associated with diabetes.
