Depression after minor stroke: prevalence and predictors.
Summary of "Depression after minor stroke: prevalence and predictors."
Background and purpose:â€‚ Post-stroke depression (PSD) is one of the most frequent complications of stroke, with a prevalence ranging 20-60%. As PSD seems to be related to stroke severity, we hypothesized that the prevalence of PSD would be lower in patients with minor stroke. Methods:â€‚ We investigated the prevalence and predictors of PSD over a 30-month follow-up period in a cohort of patients with minor ischaemic stroke (NIHSSâ€ƒâ‰¤â€ƒ5). Results:â€‚ We enrolled 105 patients (mean age 64.38â€ƒÂ±â€ƒ11.2â€ƒyears, M/F 69/36). PSD was diagnosed in 43 (41%) patients, 40 (93%) of whom had dysthymia; 22% of patients were already depressed at 1â€ƒmonth. The most frequent depressive symptoms (DSs) were working inhibition, indecisiveness, and fatigability. Patients who developed PSD were less educated (Pâ€ƒ=â€ƒ0.044) and diabetic (Pâ€ƒ=â€ƒ0.006). After excluding patients that were already depressed at 1â€ƒmonth, we performed a logistic regression model to detect predictors of PSD. Crying (Pâ€ƒ=â€ƒ0.012, OR 1.067, CI 0.269-4.553) and guilt (Pâ€ƒ=â€ƒ0.007, OR 0.037, CI 0.02Ã¬03-0.401) at baseline were two DSs found to be significantly correlated with PSD. Higher educational level (Pâ€ƒ=â€ƒ0.022, OR 0.084, CI 0.010-0.698) and diabetes (Pâ€ƒ=â€ƒ0.007, OR 14.361, CI 2.040-101.108) were the risk factors significantly correlated with PSD. Conclusion:â€‚ Post-stroke depression is frequent even in patients with minor stroke. Early detection of DSs might help to predict long-term development of PSD. No correlation was observed between lesion site or side and the development of PSD.
Clinica Neurologica A, Department of Neurology and Psychiatry, Viale dell'UniversitÃ , Rome, Italy.
This article was published in the following journal.
Name: European journal of neurology : the official journal of the European Federation of Neurological Societies
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22175796
- DOI: http://dx.doi.org/10.1111/j.1468-1331.2011.03583.x
Medical and Biotech [MESH] Definitions
Decompression external to the body, most often the slow lessening of external pressure on the whole body (especially in caisson workers, deep sea divers, and persons who ascend to great heights) to prevent DECOMPRESSION SICKNESS. It includes also sudden accidental decompression, but not surgical (local) decompression or decompression applied through body openings.
Depression in POSTPARTUM WOMEN, usually within four weeks after giving birth (PARTURITION). The degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (From DSM-IV, p386)
Minor Histocompatibility Antigens
Allelic alloantigens often responsible for weak graft rejection in cases when (major) histocompatibility has been established by standard tests. In the mouse they are coded by more than 500 genes at up to 30 minor histocompatibility loci. The most well-known minor histocompatibility antigen in mammals is the H-Y antigen.
A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
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