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Polysaccharide-K (PSK, Krestin) is one of the most commonly used medicinal mushroom extracts with a long history as an additive in cancer therapy in Asia, especially in Japan. PSK has a documented anti-tumor activity both in vitro and in vitro, in various types of cancers, including colorectal, gastric, breast, liver, pancreatic, and lung cancer. Despite PSK having been studied for about 40 years as an immune modulator and biological response modifier, the mechanisms of action by PSK have not yet been clearly and completely elucidated. This review aims to provide an up-to-date account for the effects of PSK in cancer with the hope of thereby providing an increased understanding of the molecular mechanisms of PSK and also its potential as an additive in modern cancer therapy.
Chairman, Clinical Sciences Lund, Department of Surgery, Clinical Sciences Lund, Skåne University Hospital Lund, SE-221 85 Lund, Sweden. email@example.com.
This article was published in the following journal.
Name: Current medicinal chemistry
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The act, process, or an instance of narrating, i.e., telling a story. In the context of MEDICINE or ETHICS, narration includes relating the particular and the personal in the life story of an individual.
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A composition in prose or verse presenting in dialogue or pantomime a story involving various characters, usually intended to be acted on a stage and to be regarded as a form of entertainment. (From Random House Unabridged Dictionary, 2d ed)
Glycoproteins which have a very high polysaccharide content.
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