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Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series.

12:02 EDT 18th April 2014 | BioPortfolio

Summary of "Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series."

Vulvar intraepithelial neoplasia 3 (VIN 3)/vulvar carcinoma in situ is currently treated by surgical excision, laser ablation, or topically with 5-fluorouracil or imiquimod. The rate of progression of untreated VIN 3/vulvar carcinoma in situ to invasive cancer is significant, although difficult to assess, because most patients undergo treatment. The peak incidence of invasive carcinoma of the vulva occurs in the sixth decade, which may indicate that human papillomavirus (HPV)-related preinvasive disease in the younger population has a lower progression rate. However, the risk of invasive disease cannot be disregarded.


1Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, Saint Barnabas Medical Center, Livingston; and 2Gynecologic Cancer & Pelvic Surgery LLC, West Orange, NJ.

Journal Details

This article was published in the following journal.

Name: Journal of lower genital tract disease
ISSN: 1526-0976
Pages: 56-8


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