Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L.

21:37 EDT 22nd October 2014 | BioPortfolio

Summary of "Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L."

Rhizophora mangle, the red mangrove, has long been known as a traditional antiulcer medicine. The present work evaluated the mechanisms of action involved in the anti-ulcer properties of the Rhizophora mangle bark extracts.


Departamento de Farmacologia, Faculdade de Ciências Médicas, UNICAMP, Campinas, SP, Brazil.

Journal Details

This article was published in the following journal.

Name: Journal of ethnopharmacology
ISSN: 1872-7573
Pages: 234-43


PubMed Articles [22710 Associated PubMed Articles listed on BioPortfolio]

Wind pollination and propagule formation in Rhizophora mangle L. (Rhizophoraceae): resource or pollination limitation?

Rhizophora mangle is considered as a self-compatible mangrove, and is pollinated by wind and insects. However, there is no information about fruit production by autogamy and agamospermy and on the for...

Marinobacterium mangrovicola sp. nov., a marine nitrogen-fixing bacterium isolated from mangrove roots of Rhizophora mangle.

A nitrogen-fixing marine bacterium, designated strain Gal22T, was isolated from mangrove roots of Rhizophora mangle. Cells were Gram-negative rods, motile with a single polar flagellum. Growth was obs...

Evaluation of the gastroprotective activity of the extracts, fractions, and pure compounds obtained from aerial parts of Rubus imperialis in different experimental models.

Previous phytochemical studies carried out with Rubus imperialis Chum. Schl. (Rosaceae) have demonstrated the presence of triterpenes (niga-ichigoside F1 and 2β,3β,19α-trihydroxyursolic acid) in th...

Gastroprotective effect of minocycline in experimentally induced gastric ulcers in rats.

Minocycline (MCN), a semi-synthetic tetracycline derivative possesses pleiotropic effects and provides protection against a number of disease models. However its effect on gastric ulcers has not been ...

Pharmacological correction of stress-induced gastric ulceration by novel small-molecule agents with antioxidant profile.

This study was designed to determine novel small-molecule agents influencing the pathogenesis of gastric lesions induced by stress. To achieve this goal, four novel organic compounds containing struct...

Clinical Trials [2933 Associated Clinical Trials listed on BioPortfolio]

A Study to Evaluate Safety, Side Effects, Muscle Activity and Speed of Gastric Emptying of GSK962040

Motilin is a peptide whose action is controlled by motilin receptors located in the gut. Action of Motilin at motilin receptors increases the gastric emptying rate (rate of emptying of foo...

Mechanisms of Glucose Lowering Effect of Colesvelam HCl

The mechanism by which colesevelam HCl lowers glucose is not known. Knowledge of the potential mechanism of action is important for defining the role of the drug among oral antidiabetic a...

Mechanisms Underlying Abnormal Ambulatory BP Patterns

To understand the mechanism(s) underlying sodium-dependent blood pressure control, and to determine the consequences thereof.

Tetrabenazine for Partial Responders

Purpose of Study: A) To improve outcome in large population of antipsychotic patients with schizophrenia or schizoaffective who are only partial responders B) To increase understanding of...

A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatin

Lifibrol is a new lipid-lowering drug which lowers cholesterol to an extent in the order of magnitude of the statins. The mechanism of action of this compound is different from the one of ...

Medical and Biotech [MESH] Definitions

An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that of injected gold salts, but it is better tolerated, and side effects which occur are potentially less serious.

The observable response made to a situation and the unconscious processes underlying it.

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

Search BioPortfolio: