Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L.
Summary of "Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L."
Rhizophora mangle, the red mangrove, has long been known as a traditional antiulcer medicine. The present work evaluated the mechanisms of action involved in the anti-ulcer properties of the Rhizophora mangle bark extracts.
Departamento de Farmacologia, Faculdade de Ciências Médicas, UNICAMP, Campinas, SP, Brazil.
This article was published in the following journal.
Name: Journal of ethnopharmacology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22100564
- DOI: http://dx.doi.org/10.1016/j.jep.2011.11.007
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Medical and Biotech [MESH] Definitions
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
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Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.