Transcatheter closure of the left atrial appendage: Initial experience with the amplatzer cardiac plug device.

06:00 EDT 29th July 2010 | BioPortfolio

Summary of "Transcatheter closure of the left atrial appendage: Initial experience with the amplatzer cardiac plug device."

Percutaneous left atrial appendage (LAA) closure might reduce the cardioembolic risk in those patients with nonvalvular atrial fibrillation who are not candidates for warfarin therapy. This report presents the case of two patients with atrial fibrillation who had contraindications for warfarin therapy due to bleeding complications and a high cardioembolic risk (CHADS2 >/=2) who underwent successful LAA closure with a new device, the Amplatzer Cardiac Plug. The characteristics of the device and the main technical aspects of the procedure, as well as the potential advantages of this device for LAA closure, are discussed. (c) 2010 Wiley-Liss, Inc.


Quebec Heart & Lung Institute, Laval University, Québec City, Québec, Canada.

Journal Details

This article was published in the following journal.

Name: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
ISSN: 1522-726X
Pages: 186-92


PubMed Articles [11881 Associated PubMed Articles listed on BioPortfolio]

Transcatheter Left Atrial Appendage Closure Using Intracardiac Echocardiographic Guidance From the Left Atrium.

Most commonly, left atrial appendage (LAA) occlusion procedures are performed using transesophageal echocardiography (TEE) guidance and general anaesthesia. Intracardiac echocardiography (ICE) offers ...

Feasibility and clinical efficacy of left atrial ablation for the treatment of atrial tachyarrhythmias in patients with left atrial appendage closure devices.

Left atrial appendage (LAA)-closure devices have been recently introduced as an alternative for oral anticoagulation (OAC) in patients with non-valvular atrial fibrillation (AF). Due to potential over...

Left atrial appendage closure: An emerging option in atrial fibrillation when oral anticoagulants are not tolerated.

Atrial fibrillation is associated with a risk of stroke, primarily from embolization of clots that form in the left atrial appendage. This structure has been targeted to reduce stroke risk in patients...

Left atrial appendage to great cardiac vein fistula complicating watchman left atrial appendage closure.

Left Atrial Appendage Closure.

Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA), due to both the loss of atrial systole and the unique...

Clinical Trials [2733 Associated Clinical Trials listed on BioPortfolio]

Left Atrial Appendage Closure Compared to Standard Antiplatelet Therapy in Patients With AF Who Underwent PCI

The objective of Left atrial appendage closure compared to standard antiplatelet therapy in patients with AF who underwent percutaneous coronary intervention (LLA-PCI) study is to evaluate...

French Database of Left Atrial Appendage Closure

Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms. This justifies the prescription ...

Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage

The purpose of this study is to evaluate the performance of the Cardioblate Closure Device to occlude the LAA

Left Atrial Volume Index and Left Atrial Appendage Flow Velocities

After obtaining a consent, bed side cardiac ultrasonography will be performed for cases undergoing transesophageal echocardiography to evaluate the correlation between left atrium volume a...

Impact of Left Atrial Appendage Exclusion on Short-Term Clinical Outcomes and Long-Term Stroke Incidence

Stroke is a major cause of morbidity in western society, and an infrequent complication of cardiac surgery. The majority of thromboembolic strokes arise from the left atrium, in particular...

Medical and Biotech [MESH] Definitions

Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed)

The hemodynamic and electrophysiological action of the LEFT ATRIUM.

Absence of the orifice between the RIGHT ATRIUM and RIGHT VENTRICLE, with the presence of an atrial defect through which all the systemic venous return reaches the left heart. As a result, there is left ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR) because the right ventricle is absent or not functional.

Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).


Relevant Topics

Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza,  Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...

Searches Linking to this Article