Palladium-Catalyzed Oxidative Heck Coupling Reaction for Direct Synthesis of 4-Arylcoumarins Using Coumarins and Arylboronic Acids.

05:14 EDT 24th May 2015 | BioPortfolio

Summary of "Palladium-Catalyzed Oxidative Heck Coupling Reaction for Direct Synthesis of 4-Arylcoumarins Using Coumarins and Arylboronic Acids."

An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4-Arylcoumarins were obtained in moderate to excellent yields, and the reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.

Affiliation

State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology , Dalian 116024, China.

Journal Details

This article was published in the following journal.

Name: The Journal of organic chemistry
ISSN: 1520-6904
Pages:

Links

PubMed Articles [18528 Associated PubMed Articles listed on BioPortfolio]

Palladium-Catalyzed Oxidative Heck-Type Alkylation/Aryl Migration/Desulfonylation between Alkenes with α-Carbonyl Alkyl Bromides.

A new Pd(II)-catalyzed alkene oxidative difunctionalization initiated by Heck insertion has been developed for the selective synthesis of acyclic and cyclic all-carbon quaternary stereocenters, which ...

A New Efficient Stereoselective Method for the Synthesis of (E)-5-Aminoallyl-Pyrimidine-5'-Triphosphates Using Palladium-Catalyzed Heck Reaction.

An efficient overall two-step strategy for the synthesis of (E)-5-aminoallyl-pyrimidine-5'-triphoshate, starting from commercially available pyrimidine-5'-triphosphate is described. The method involve...

Synthesis of Quinolinones with Palladium-Catalyzed Oxidative Annulation between Acrylamides and Arynes.

An unprecedented palladium-catalyzed oxidative annulation of acrylamides with benzyne precursors has been successfully developed. By using this mild "N-H activation/Heck reaction" method, a wide varie...

Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of alpha-Diazo Phosphonates with Benzyl or Allyl Halides.

An efficient method for the synthesis of organophosphonates through palladium-catalyzed coupling of alpha-diazo phosphonates with benzyl or allyl halides has been developed. Trisubstituted alkenylphos...

Pd-catalyzed steroid reactions.

We review the most important achievements of the last decade in the field of steroid synthesis in the presence of palladium catalysts. Various palladium-catalyzed cross-coupling reactions, including H...

Clinical Trials [1427 Associated Clinical Trials listed on BioPortfolio]

A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Cholesterol is the precursor of glucocorticoids, mineralocorticoids and sex steroids. Both adrenal and non-adrenal (ovarian + testicular) all steroid hormones are primarily synthesized usi...

Study of the Ability of Clarithromycin to Induce Oxidative Stress

The purpose of the study is to examine whether Klacid® (Clarithromycin) will induce oxidative stress (stress from oxygen) in healthy subjects. This is done by measuring the content of a p...

Cardioventilatory Coupling in Critically Ill Patients

This study measures the cardioventilatory coupling in critically ill patients during mechanical ventilation in controlled mode (pressure controlled) and in patient-driven mode (pressure su...

Neurovascular Coupling in Patients With Early Stage Diabetes Retinopathy

A variety of studies demonstrate that ocular blood flow is altered in diabetes and retinal perfusion abnormalities have been proposed to contribute to the pathogenesis of diabetic retinopa...

Effect of Nutrition on Muscle Protein Synthesis

The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that m...

Medical and Biotech [MESH] Definitions

The reaction of two molecular entities via oxidation usually catalyzed by a transition metal compound and involving dioxygen as the oxidant.

The fusion of ceramics (porcelain) to an alloy of two or more metals for use in restorative and prosthodontic dentistry. Examples of metal alloys employed include cobalt-chromium, gold-palladium, gold-platinum-palladium, and nickel-based alloys.

A carbodiimide that is used as a chemical intermediate and coupling agent in peptide synthesis. (From Hawley's Condensed Chemical Dictionary, 12th ed)

A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.

Search BioPortfolio:
Loading
Advertisement
Advertisement

Searches Linking to this Article