Impact of a region wide antimicrobial stewardship guideline on urinary tract infection prescription patterns.

13:45 EDT 28th July 2015 | BioPortfolio

Summary of "Impact of a region wide antimicrobial stewardship guideline on urinary tract infection prescription patterns."

Background Fluoroquinolones are frequently prescribed for non complicated urinary tract infection treatments and have a negative ecological impact. We aimed to substitute them by antibiotics with narrower activity spectrum in order to preserve fluoroquinolone activity in complicated hospital infections. Objective To assess the impact of a multi-modal approach that combines the dispatching of antibiotic prescription guidelines and voluntary attendance at educational sessions on general practitioners' (GP) antibiotic prescription habits. Setting This study was led in Franche-Comté, a French eastern region, where GPs were given a guideline recommending a restricted use of fluoroquinolones for urinary tract infections. Method Segmented regression analysis of interrupted time series was used to assess changes in antibiotic prescription. Main outcome measure: The antibiotic prescription data of nitrofurantoin, fosfomycin-trometamol and fluoroquinolones for women aged 15-65 years were obtained from the regional agency of health insurance. Results Twenty months after intervention, the number of nitrofurantoin and fosfomycintrometamol prescriptions increased by 36.8% (95%
CI:
30.6-42.2) and 28.5% (95%
CI:
22.9-35.4), respectively, while that of norfloxacin decreased by 9.1% (95%
CI:
-15.3 to -3.5). Conclusion This study suggests that the dispatch of the guideline on urinary tract infection had a moderate impact on antibiotic prescriptions.

Affiliation

Service d'Hygiène Hospitalière, Centre Hospitalier Universitaire Besançon, 3 Bd Fleming, 25030, Besancon, Cedex, France.

Journal Details

This article was published in the following journal.

Name: International journal of clinical pharmacy
ISSN: 2210-7711
Pages:

Links

PubMed Articles [20260 Associated PubMed Articles listed on BioPortfolio]

Comparative prevalence of antimicrobial resistance in community-acquired urinary tract infection cases from representative States of northern and southern India.

Urinary tract infections (UTIs) are amongst the most common infections described in outpatient settings. Increased antimicrobial resistance (AMR) of urinary tract pathogens is a matter of global publi...

Long-term effects of an antimicrobial stewardship programme at a tertiary-care teaching hospital.

Antimicrobial stewardship has been shown to reduce unnecessary antibiotic use, but there are few data on the long-term benefits of such a programme. Antimicrobial use over a 13-year period since imple...

Neonatal Staphylococcus lugdunensis urinary tract infection.

Staphylococcus lugdunensis is a known pathogen of infective endocarditis, but not of urinary tract infection. We report a previously healthy neonate without congenital anomalies of the kidney and urin...

Point-of-Prescription Interventions to Improve Antimicrobial Stewardship.

Antimicrobial stewardship is pivotal to improving patient outcomes, reducing adverse events, decreasing healthcare costs, and preventing further emergence of antimicrobial resistance. In an era in whi...

An international cross-sectional survey of antimicrobial stewardship programmes in hospitals.

To report the extent and components of global efforts in antimicrobial stewardship (AMS) in hospitals.

Clinical Trials [2927 Associated Clinical Trials listed on BioPortfolio]

Improving Antibiotic Use in Hospitalized Patients With Pneumonia

The purpose of the study is to determine whether an antimicrobial stewardship program can decrease the length of hospital stay for patients with pneumonia. The antimicrobial stewardship p...

Antimicrobial Stewardship in Pediatric Surgery

Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy. Although guidelines and recommendations e...

Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin

The information collected will optimize the management of patients with urinary tract infections with secondary bacteremia, primarily with gram negative bacteria especially Escherichia co...

Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit

The purpose of this study is to identify risk factors associated with indwelling urinary catheters, as well as to assess the nurses' knowledge and adherence to hospital policies. The study...

The Causes and Interpretation of Low-level Resistance in Staphylococcus Aureus

The hypothesis of this investigation is that rate of isolation of resistant nosocomial pathogens can be explained by a combination of measures that include, among other things, antimicrobi...

Medical and Biotech [MESH] Definitions

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.

A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.

Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.

Properties, functions, and processes of the URINARY TRACT as a whole or of any of its parts.


Advertisement
 

Relevant Topics

Urology
Latest News Clinical Trials Research Drugs Reports Corporate
Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...

Infectious-diseases
Latest News Clinical Trials Research Drugs Reports Corporate
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...

Women's Health
Latest News Clinical Trials Research Drugs Reports Corporate
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Advertisement
 

Searches Linking to this Article