Development of a Minimally Invasive, Injectable, Shape Memory Suture and Delivery System.
Summary of "Development of a Minimally Invasive, Injectable, Shape Memory Suture and Delivery System."
Suturing in space-confined surgical settings encountered during microsurgical procedures can be technically complex and time intensive. This paper presents the development of a new injector and new shape-memory alloy clip that can replace conventional suture. Engineering and surgical assessments of the injector and clips were performed. A prototype of the delivery system was tested in simulated surgical settings and compared to conventional suturing techniques for surgical time and wound strength. In various micro-surgical scenarios, the new injectable system proved to be 5 to 20-times more efficient and to have wound strengths over three-times that of conventional suturing. Further, the wounds closed by the shape-memory alloy clips could be forced to open and then recover to a watertight state, unlike conventional sutures which break upon failure. This new injector and shape-memory alloy clips proved to be quicker, stronger, and technically easier than conventional suturing. Future work is underway to test the injectable delivery system and the shape-memory alloy clips using a real-time, in vivo porcine model.
Affiliation
Department of Ophthalmology, School of Medicine, University of Colorado Denver, 1675 Aurora Ct, Mail Stop 731, Aurora, CO, 80045, USA.
Journal Details
This article was published in the following journal.
Name: Annals of biomedical engineering
ISSN: 1521-6047
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22258886
- DOI: http://dx.doi.org/10.1007/s10439-012-0508-5
Medical and Biotech [MESH] Definitions
Surgical Procedures, Minimally Invasive
Procedures that avoid use of open invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device. With the reduced trauma associated with minimally invasive surgery, long hospital stays may be reduced with increased rates of short stay or day surgery.
Plagiocephaly
The condition characterized by uneven or irregular shape of the head often in parallelogram shape with a flat spot on the back or one side of the head. It can either result from the premature CRANIAL SUTURE closure (CRANIOSYNOSTOSIS) or from external forces (NONSYNOSTOTIC PLAGIOCEPHALY).
Ultrasonography, Interventional
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Endovascular Procedures
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
Magnetic Resonance Imaging, Interventional
Minimally invasive procedures guided with the aid of magnetic resonance imaging to visualize tissue structures.
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