A reverse-ELISA for the detection of TRIM28/KAP1 serum autoantibodies in colorectal cancer patients.
Summary of "A reverse-ELISA for the detection of TRIM28/KAP1 serum autoantibodies in colorectal cancer patients."
No Summary Available
Affiliation
Department of Physiology and Medical Physics , 123 Saint Stephen's Green, Dublin 2 , Ireland.
Journal Details
This article was published in the following journal.
Name: Acta oncologica (Stockholm, Sweden)
ISSN: 1651-226X
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22268577
- DOI: http://dx.doi.org/10.3109/0284186X.2011.652742
Medical and Biotech [MESH] Definitions
Coombs' Test
Hemagglutination test in which Coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means).
Hiv Core Protein P24
A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by ELISA and Western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines.
Hepatitis, Autoimmune
A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES.
Hashimoto Disease
Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.
Aberrant Crypt Foci
Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.
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