Primary intracranial leiomyosarcoma in an HIV-infected patient.
Summary of "Primary intracranial leiomyosarcoma in an HIV-infected patient."
Primary intracranial leiomyosarcomas are rare tumors arising from the mesenchymal cells of the dura matter or the cerebral blood vessels. Only 14 cases of primary intracranial leiomyosarcoma are reported in the literature. We report a case of primary intracranial leiomyosarcoma in an human immunodeficiency virus-positive patient with a CD4 count of 14 cells/muL. Additionally, in-situ hybridization of Epstein-Barr virus (EBV) early RNA stained sections highlighted the tumor cells, consistent with the presence of EBV. Review of the literature strongly suggests an association between AIDS, EBV, and primary intracranial leiomyosarcoma. Given the paucity of information in the literature, we review possible chemotherapeutic agents for treatment of primary intracranial leiomyosarcoma in patients refractory to surgical resection and radiation therapy.
Affiliation
Tisch Cancer Institute, The Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1079, New York, NY, 10029, USA, shanthi.sivendran@mssm.edu.
Journal Details
This article was published in the following journal.
Name: International journal of clinical oncology / Japan Society of Clinical Oncology
ISSN: 2547-7772
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20676716
- DOI: http://dx.doi.org/10.1007/s10147-010-0110-5
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The primary responsibility of one nurse for the planning, evaluation, and care of a patient throughout the course of illness, convalescence, and recovery.
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