Positive impact of levetiracetam on emotional learning and memory in naive mice.
Summary of "Positive impact of levetiracetam on emotional learning and memory in naive mice."
The effect of an antiepileptic drug on cognitive function is of primary importance with respect to the patient's quality of life. Levetiracetam (LEV) is a novel antiepileptic drug used to treat epilepsy, but its effects on spatial and emotional learning and memory are not yet well understood. The goal of our study was to establish the effects of LEV (17 and 54mg/kg, intraperitoneally (IP)) on spatial memory retrieval in the Morris water maze test and on acquisition and memory formation in the passive avoidance (PA) test in naive mice.
Kocaeli University, Department of Pharmacology, Faculty of Medicine, Psychopharmacology Laboratory, 41380, Kocaeli, Umuttepe, Turkey.
This article was published in the following journal.
Name: Life sciences
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22119754
- DOI: http://dx.doi.org/10.1016/j.lfs.2011.11.003
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