Common Neuropathic Itch Syndromes.
Summary of "Common Neuropathic Itch Syndromes."
Patients with chronic itch are diagnosed and treated by dermatologists. However, itch is a neural sensation and some forms of chronic itch are the presenting symptoms of neurological diseases. Dermatologists need some familiarity with the most common neuropathic itch syndromes to initiate diagnostic testing and to know when to refer to a neurologist. This review summarizes current knowledge, admittedly incomplete, on neuropathic itch caused by diseases of the brain, spinal cord, cranial or spinal nerve-roots, and peripheral nerves.
Affiliation
Department of Neurology, Massachusetts General Hospital, 275 Charles Street, Boston, MA 02114, USA. E-mail: aoaklander@partners.org.
Journal Details
This article was published in the following journal.
Name: Acta dermato-venereologica
ISSN: 1651-2057
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22307048
- DOI: http://dx.doi.org/10.2340/00015555-1318
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PubMed Articles
VGLUT2-Dependent Glutamate Release from Nociceptors Is Required to Sense Pain and Suppress Itch.
Itch can be suppressed by painful stimuli, but the underlying neural basis is unknown. We generated conditional null mice in which vesicular glutamate transporter type 2 (VGLUT2)-dependent synaptic gl...
Chronic itch affects millions of patients worldwide and has a significant impact on quality of life. The assessment of itch and its associated effects is a significant component of clinical practice i...
VGLUT2-Dependent Sensory Neurons in the TRPV1 Population Regulate Pain and Itch.
The natural response to itch sensation is to scratch, which relieves the itch through an unknown mechanism. Interaction between pain and itch has been frequently demonstrated, and the selectivity hypo...
Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch.
ABSTRACT: BACKGROUND: Herpes simplex virus type 2 (HSV-2) is one of many viruses that exploits and modifies the cellular ubiquitin system. HSV-2 expresses the tegument protein UL56 that has been impli...
The association between itch and suicidal ideation has not been explored previously in the general population. The aim of the present study is to analyse the association between itch and suicidal idea...
Clinical Trials
The Effect of Visual Stimuli on Itch Perception Intensity in Healthy and Atopic Dermatitis Patients
The purpose of this research study is to assess whether seeing other people itch affects itch perception in patients with atopic dermatitis and healthy subjects.
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. Treatment of neuropathic pain often requires a combination of pain medications due to...
To establish the infrastructure for a national neuropathic pain database. To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability...
Efficacy of Cortex Stimulation in Neuropathic Pain
The pains chronic neurogeneses remain difficult to treat whatever are their origin and their localization. The pharmacological therapeutic arsenal answers only partially the symptomatolog...
Impact of Oral Magnesium on Neuropathic Pain
Use lay language. The aim of this study is to evaluate on pain scores (neuropathic pain questionnaire and pain numeric scale) and on quality of life, the effect of oral magnesium intake o...
