The effectiveness of a calcium sodium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity: a pilot study.

11:33 EDT 25th May 2015 | BioPortfolio

Summary of "The effectiveness of a calcium sodium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity: a pilot study."

NovaMin (NovaMin Technology, Alachua, Fla.) was introduced into the dental market as a desensitizer in December 2004. However, to the authors' knowledge, no researchers yet have evaluated the effectiveness of 100 percent NovaMin powder with NovaMin-containing toothpaste in reducing dentin hypersensitivity compared with the effectiveness of NovaMin-containing toothpaste only and a desensitizing toothpaste containing potassium nitrate as a control.
The authors divided 60 participants randomly into three groups: NovaMin powder with NovaMin-containing toothpaste (group 1), a placebo powder with NovaMin-containing toothpaste (group 2) and a placebo powder with the control toothpaste (group 3). The authors used tactile and cold stimuli and a visual analog scale to evaluate participants' pain at baseline, immediately after powder application and at one week, two weeks and four weeks after powder application. They analyzed data by using Friedman and Wilcoxon signed-rank tests for within-group comparison. They used Kruskal-Wallis and Mann-Whitney U tests for between-group comparison. They considered P < .05 to be statistically significant.
Groups 1 and 2 showed significant hypersensitivity reduction over baseline at all time points. Group 3 showed significant hypersensitivity reduction at one week onward. Group 1 showed significant improvement compared with groups 2 and 3, except for response to tactile stimulus at four weeks with group 2. Between groups 2 and 3, there were significant differences at two and four weeks.
The use of NovaMin powder and NovaMin-containing toothpaste for hypersensitivity reduction is more effective than the use of a desensitizing toothpaste containing potassium nitrate and fluoride.


Journal Details

This article was published in the following journal.

Name: Journal of the American Dental Association (1939)
ISSN: 1943-4723
Pages: 995-9


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Medical and Biotech [MESH] Definitions

Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.

An electrogenic ion exchange protein that maintains a steady level of calcium by removing an amount of calcium equal to that which enters the cells. It is widely distributed in most excitable membranes, including the brain and heart.

An apparently hereditary disorder of dentin formation, marked by a normal appearance of coronal dentin associated with pulpal obliteration, faulty root formation, and a tendency for peripheral lesions without obvious cause. (From Dorland, 27th ed)

Dentin formed by normal pulp after completion of root end formation.

The susceptibility of the DENTIN to dissolution.

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