Hypercalcemia Due to Subcutaneous Fat Necrosis in a Newborn After Total Body Cooling.
Summary of "Hypercalcemia Due to Subcutaneous Fat Necrosis in a Newborn After Total Body Cooling."
  Subcutaneous fat necrosis is an inflammatory disorder of adipose tissue. Although patients need long-term follow-up to prevent hypercalcemia, the prognosis is generally favorable. We herein present a case of a newborn who developed subcutaneous fat necrosis-related hypercalcemia after hypothermia treatment for hypoxic ischemic encephalopathy. Widespread use of hypothermia treatment for hypoxic ischemic encephalopathy in the neonatal intensive care unit may increase the risk of developing subcutaneous fat necrosis and subsequently hypercalcemia. Great care should be taken to recognize skin findings early in newborns receiving hypothermia treatment, and those diagnosed with subcutaneous fat necrosis require close follow-up because they are at risk for developing hypercalcemia.
Affiliation
Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey.
Journal Details
This article was published in the following journal.
Name: Pediatric dermatology
ISSN: 1525-1470
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22352980
- DOI: http://dx.doi.org/10.1111/j.1525-1470.2011.01716.x
Medical and Biotech [MESH] Definitions
Cryoanesthesia
ANESTHESIA achieved by lowering either BODY TEMPERATURE (core cooling) or SKIN TEMPERATURE (external cooling).
Subcutaneous Emphysema
Presence of air or gas in the subcutaneous tissues of the body.
Skinfold Thickness
The measurement of subcutaneous fat located directly beneath the skin by grasping a fold of skin and subcutaneous fat between the thumb and forefinger and pulling it away from the underlying muscle tissue. The thickness of the double layer of skin and subcutaneous tissue is then read with a caliper. The five most frequently measured sites are the upper arm, below the scapula, above the hip bone, the abdomen, and the thigh. Its application is the determination of relative fatness, of changes in physical conditioning programs, and of the percentage of body fat in desirable body weight. (From McArdle, et al., Exercise Physiology, 2d ed, p496-8)
Rheumatoid Nodule
Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.
Body Burden
The total amount of a chemical, metal or radioactive substance present at any time after absorption in the body of man or animal.
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