Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

13:09 EDT 28th August 2015 | BioPortfolio

Summary of "Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes."

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC(50) = 1.32-0.38 μg/ml) and α-amylase (IC(50) = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC(50) = 0.28 μg) and α-amylase (IC(50) = 24.5 μg) inhibition.

Affiliation

Agroprocessing and Natural Products Division, National Institute for Interdisciplinary Science and Technology (CSIR) , Thiruvananthapuram, Kerala , India.

Journal Details

This article was published in the following journal.

Name: International journal of food sciences and nutrition
ISSN: 1465-3478
Pages:

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Medical and Biotech [MESH] Definitions

A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.

A plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).

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Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.


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