Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

06:00 EST 6th March 2012 | BioPortfolio

Summary of "Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes."

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC(50) = 1.32-0.38 μg/ml) and α-amylase (IC(50) = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC(50) = 0.28 μg) and α-amylase (IC(50) = 24.5 μg) inhibition.


Agroprocessing and Natural Products Division, National Institute for Interdisciplinary Science and Technology (CSIR) , Thiruvananthapuram, Kerala , India.

Journal Details

This article was published in the following journal.

Name: International journal of food sciences and nutrition
ISSN: 1465-3478


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Medical and Biotech [MESH] Definitions

A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.

A plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).

Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.

A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.

Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.


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