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Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC(50) = 1.32-0.38 μg/ml) and α-amylase (IC(50) = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC(50) = 0.28 μg) and α-amylase (IC(50) = 24.5 μg) inhibition.
Agroprocessing and Natural Products Division, National Institute for Interdisciplinary Science and Technology (CSIR) , Thiruvananthapuram, Kerala , India.
This article was published in the following journal.
Name: International journal of food sciences and nutrition
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Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.
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