Long-term outcomes of endonasal surgery for choanal atresia: 28 years experience in an academic medical centre.
Summary of "Long-term outcomes of endonasal surgery for choanal atresia: 28 years experience in an academic medical centre."
This study aimed to evaluate the long-term outcomes of endonasal surgical treatment for choanal atresia (CA) and determine possible predictors of recurrence. A retrospective study of 50 cases of CA that were managed endonasally was conducted at an academic tertiary referral centre. Recurrence of disease was assessed with regard to the type and nature of atresia, presence of CHARGE association and stent usage. Bilateral CA cases (n = 76 sides) were operated at an early age and had an incidence of recurrence of 57%, while unilateral cases had a recurrence rate of 25% (3/12). Use of stents did not have a statistically significant effect on the rate of recurrence. However, a significantly higher recurrence rate was noted in patients with purely bony atretic plates (p < 0.001) or CHARGE association (p = 0.049). A tendency towards a higher recurrence rate in bilateral atresias was also found (p = 0.085). The transnasal approach is a safe and effective way to re-establish the nasal choanae. However, appropriate information on the likelihood of recurrence should be included in the preoperative counselling of patients and their parents, especially in cases with bilateral atresia or CHARGE association.
Affiliation
Department of Otolaryngology-Head and Neck Surgery, University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany, stylianos.velegrakis@uk-erlangen.de.
Journal Details
This article was published in the following journal.
Name: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (
ISSN: 1434-4726
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22392520
- DOI: http://dx.doi.org/10.1007/s00405-012-1982-y
Medical and Biotech [MESH] Definitions
Choanal Atresia
A congenital abnormality that is characterized by a blocked CHOANAE, the opening between the nose and the NASOPHARYNX. Blockage can be unilateral or bilateral; bony or membranous.
Memory, Short-term
Temporary storage of information for a few seconds to hours, as opposed to long-term memory which refers to material stored for days, years, or a lifetime.
Memory, Long-term
Remembrance of information from 3 or more years previously.
Charge Syndrome
Rare disease characterized by COLOBOMA; CHOANAL ATRESIA; and abnormal SEMICIRCULAR CANALS. Mutations in CHD7 protein resulting in disturbed neural crest development are associated with CHARGE Syndrome.
Insurance, Long-term Care
Health insurance to provide full or partial coverage for long-term home care services or for long-term nursing care provided in a residential facility such as a nursing home.
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