Local staging of prostate cancer with MRI.
Summary of "Local staging of prostate cancer with MRI."
Accurate local staging of prostate cancer is essential for patient management decisions. Conventional and evolving magnetic resonance imaging (MRI) techniques, such as diffusion-weighted imaging, dynamic contrast-enhanced MRI, and MR spectroscopy, are promising techniques in prostate cancer imaging. In this article, we will review the current applications of conventional and advanced MRI techniques in the local staging of prostate cancer.
Affiliation
Department of Radiology, University of Chicago, Chicago, Illinois, USA.
Journal Details
This article was published in the following journal.
Name: Diagnostic and interventional radiology (Ankara, Turkey)
ISSN: 1305-3612
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22399364
- DOI: http://dx.doi.org/10.4261/1305-3825.DIR.4970-11.2
Medical and Biotech [MESH] Definitions
Prostate-specific Antigen
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Fenretinide
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Ultrasound, High-intensity Focused, Transrectal
Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).
Prostatic Secretory Proteins
Proteins secreted by the prostate gland. The major secretory proteins from the human prostate gland include PROSTATE-SPECIFIC ANTIGEN, prostate-specific acid phosphatase, prostate-specific membrane antigen, and prostate-specific protein-94.
Prostatic Neoplasms
Tumors or cancer of the PROSTATE.
PubMed Articles
MRI of localized prostate cancer: coming of age in the PSA era.
Prostate cancer is the most common cancer among American men. It varies widely in aggressiveness, ranging from completely indolent to highly aggressive. Currently, predicting the natural history of a...
Castration-resistant prostate cancer is the second most common cause of cancer death and results in a median survival of less than 2 years. In prostate cancer, fusions between TMPRSS2 and ERG are com...
Nondetectable prostate cancer in radical prostatectomy specimens.
Since the widespread use of prostate-specific antigen, early diagnosis of prostate cancer at an early stage has been increased. Consequently, a greater frequency of low-volume disease or no tumor has...
Traversing the genomic landscape of prostate cancer from diagnosis to death.
The clinical spectrum of prostate cancer ranges from curable, local disease to widely metastatic, lethal cancer. Two new prostate cancer genome studies provide the first glimpse at both ends of this s...
This article provides an overview of imaging modalities that aid in diagnosing, staging, and assessing therapeutic response in prostate cancer. Prostate cancer is the second most common type of cancer...
Clinical Trials
Characterization of Prostate Cancer With 3T MR
The long-term goal of this proposal is to provide a pre-treatment evaluation that can assist in the rational selection of patients to undergo appropriate and definitive therapy for prostat...
MDX-010 for Advanced Prostate Cancer
A total of 108 males with advanced prostate cancer will be enrolled into this study. Patients must have undergone prostate cancer staging within 180 days of enrollment. 54 patients will b...
The objective of this trial is to assess the value of 18F-choline PET/CT for the detection of regional lymph node metastases from prostate cancer. In addition, the investigators want to ev...
The aim of this study is the improvement of primary diagnostics of patients with prostate cancer by detecting cancer tissue and metastasis (in lymph nodes and other organs) with Choline-PE...
The purpose of this study is to determine the ability of functional MRI techniques [High Resolution Dynamic Contrast Enhanced MRI (HR-DCE-MRI), diffusion weighted MRI (DWI) and BOLD MRI] t...