Coexistence of psoriasis and bullous pemphigoid: remission with low-dose methotrexate.
Summary of "Coexistence of psoriasis and bullous pemphigoid: remission with low-dose methotrexate."
The coexistence of psoriasis vulgaris and bullous pemphigoid is rare. Here, we report a 90-year-old patient with a 20-year history of psoriasis. She developed vesicles and bullae suddenly and was diagnosed as bullous pemphigoid. Low-dose methotrexate therapy quickly cleared both psoriatic and bullous lesions.
Department of Dermatology, Celal Bayar University , Manisa , Turkey.
This article was published in the following journal.
Name: Cutaneous and ocular toxicology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22429144
- DOI: http://dx.doi.org/10.3109/15569527.2012.667030
Medical and Biotech [MESH] Definitions
An itching, autoimmune, bullous SKIN disease that occurs during the last two trimesters of PREGNANCY and PUERPERIUM. It also affects non-pregnant females with tissue of PLACENTA origin, such as CHORIOCARCINOMA; or HYDATIDIFORM MOLE. It exhibits antigenic and clinical similarity to bullous pemphigoid (PEMPHIGOID, BULLOUS). This disease does not involve herpes viruses (old name, herpes gestationis).
A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Lethal Dose 50
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
Pemphigoid, Benign Mucous Membrane
A chronic blistering disease with predilection for mucous membranes and less frequently the skin, and with a tendency to scarring. It is sometimes called ocular pemphigoid because of conjunctival mucous membrane involvement.
Abstract is missing (Letter).
Introduction. We present here results of methotrexate, in term of efficacy and tolerance, administrated in 21 Tunisian patients with severe psoriasis. Methods. It was a retrospective study conducted b...
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