Is penile atherosclerosis the link between erectile dysfunction and cardiovascular risk? An autopsy study.

15:49 EDT 31st August 2015 | BioPortfolio

Summary of "Is penile atherosclerosis the link between erectile dysfunction and cardiovascular risk? An autopsy study."

Erectile dysfunction (ED) is increasingly linked to coronary heart disease risk. Aim of this study was to test the hypothesis whether this association is due to penile atherosclerosis. We evaluated the prevalence and severity of penile atherosclerosis in relation to coronary and peripheral atherosclerosis. Between January and June 2010, a consecutive series of 31 men underwent an autopsy at the Department of Pathology at the Medical University Vienna. Atherosclerosis at the following localizations were histologically classified: right coronary artery, left coronary artery, left circumflex artery, internal iliac artery, dorsal penile artery and deep penile artery (bilateral). Coronary and peripheral atherosclerosis was present in 87.1 and 77.4% of cases. Atherosclerosis of penile arteries was detectable in only 4 men (12.9%). The only factor linked to penile atherosclerosis was diabetes (P=0.03). All other parameters as assessed according to medical history, general finding from autopsy or histological results regarding arterial lesions in general were not correlated to penile arterial lesions. In contrast to the high prevalence of atherosclerosis in general, penile arterial lesions are rarely present.International Journal of Impotence Research advance online publication, 22 March 2012; doi:10.1038/ijir.2012.3.

Affiliation

Department of Urology and Andrology, Hospital Saint John of God, Academic Teaching Hospital, Vienna Medical School, Vienna, Austria.

Journal Details

This article was published in the following journal.

Name: International journal of impotence research
ISSN: 1476-5489
Pages:

Links

PubMed Articles [19224 Associated PubMed Articles listed on BioPortfolio]

Tadalafil therapy for erectile dysfunction following prostatectomy.

Erectile dysfunction is a major complication affecting the quality of life of patients and partners after radical prostatectomy. Evolving evidence suggests that early penile rehabilitation may provide...

Erectile dysfunction and cardiovascular disease.

Abstract Erectile dysfunction (ED) is often a comorbid condition commonly associated with cardiovascular disease (CVD). It is important for physicians to understand that the relationship between ED an...

Erectile dysfunction is associated with low total serum testosterone levels and impaired flow-mediated vasodilation in intermediate risk men according to the framingham risk score.

Background: The role erectile dysfunction (ED) coupled with low testosterone levels as early markers of atherosclerosis is not well understood. Objectives: To analyze the relationship between serum te...

Erectile dysfunction and coronary heart disease.

This narrative review discusses the associations of erectile dysfunction with coronary heart disease (CHD) morbidity and mortality, all-cause death and CHD risk factors. Treatment strategies for erect...

Possible Association between Erectile Dysfunction and Osteoporosis in Men.

Sexual dysfunction in general and erectile dysfunction (ED) in particular significantly affect men's quality of life. Some patients who have ED, also develop osteoporosis. So, in this study we investi...

Clinical Trials [4774 Associated Clinical Trials listed on BioPortfolio]

Improvement of Erectile Dysfunction by Fluvastatin in Patients With Cardiovascular Risk Factors

The purpose of the study is to determine the effect of fluvastatin on penile arterial blood flow and erectile function in patients with arteriogenic ED and cardiovascular risk factors.

Evaluate Improvement of Erectile Dysfunction After Placement of the AMS IPP 2005 Inflatable Penile Prosthesis

The purpose of this study is to assess the American Medical System's IPP 2005 inflatable penile prosthesis implant in subjects receiving the implant for erectile dysfunction for ease of pa...

Evaluation of the Coloplast Titan IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)

This study is designed to assess the effectiveness of the Coloplast Titan Inflatable Penile Prosthesis (IPP) at maintaining or increasing penile length after implantation of the device. It...

A Randomized, Open-Label, Crossover, Multicenter, Single Dose Comparator Study Evaluating Onset Of Penile Rigidity In Men With Erectile Dysfunction Who Are Treated With Sildenafil And Tadalafil

The objective of this study was to determine and compare the minimum time required to achieve penile rigidity greater than or equal to 60% at the base of the penis that is sustained for at...

Titan One Touch Release Inflatable Penile Prosthesis

The purpose of this study is to assess the ease of deflation of the Titan OTR pump.

Medical and Biotech [MESH] Definitions

The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.

Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.

Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.

Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.

Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.


Advertisement
 

Relevant Topic

Cardiology
Latest News Clinical Trials Research Drugs Reports Corporate
Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Advertisement
 

Searches Linking to this Article