Is penile atherosclerosis the link between erectile dysfunction and cardiovascular risk? An autopsy study.
Summary of "Is penile atherosclerosis the link between erectile dysfunction and cardiovascular risk? An autopsy study."
Erectile dysfunction (ED) is increasingly linked to coronary heart disease risk. Aim of this study was to test the hypothesis whether this association is due to penile atherosclerosis. We evaluated the prevalence and severity of penile atherosclerosis in relation to coronary and peripheral atherosclerosis. Between January and June 2010, a consecutive series of 31 men underwent an autopsy at the Department of Pathology at the Medical University Vienna. Atherosclerosis at the following localizations were histologically classified: right coronary artery, left coronary artery, left circumflex artery, internal iliac artery, dorsal penile artery and deep penile artery (bilateral). Coronary and peripheral atherosclerosis was present in 87.1 and 77.4% of cases. Atherosclerosis of penile arteries was detectable in only 4 men (12.9%). The only factor linked to penile atherosclerosis was diabetes (P=0.03). All other parameters as assessed according to medical history, general finding from autopsy or histological results regarding arterial lesions in general were not correlated to penile arterial lesions. In contrast to the high prevalence of atherosclerosis in general, penile arterial lesions are rarely present.International Journal of Impotence Research advance online publication, 22 March 2012; doi:10.1038/ijir.2012.3.
Department of Urology and Andrology, Hospital Saint John of God, Academic Teaching Hospital, Vienna Medical School, Vienna, Austria.
This article was published in the following journal.
Name: International journal of impotence research
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22437107
- DOI: http://dx.doi.org/10.1038/ijir.2012.3
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Medical and Biotech [MESH] Definitions
The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.
Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.
Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.
Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.
Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.