Treatment of recalcitrant viral warts with pulsed dye laser MAL-PDT.
Summary of "Treatment of recalcitrant viral warts with pulsed dye laser MAL-PDT."
Abstract Background: Photodynamic therapy (PDT) has been explored for the treatment of recalcitrant viral warts (VW) with good results in recent publications. Methods: We carried out a descriptive and observational study in 19 patients with recalcitrant VW. Methyl aminolaevulinic acid (MAL) was occluded for 3 hours and pulsed dye laser (PDL) was used as the light source. VW were treated weekly until they were clear or for a maximum of six sessions. Results: A total of 53% of the VW cleared, and 26% of the patients demonstrated complete clearance of all their VW. The treatment was well tolerated and no adverse events were recorded. Conclusions: PDL-PDT is an effective and well-tolerated treatment option for patients with recalcitrant VW. Though only half of patients show any improvement, responders are likely to show complete clearance of their warts.
Affiliation
Dermatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Journal Details
This article was published in the following journal.
Name: The Journal of dermatological treatment
ISSN: 1471-1753
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20673158
- DOI: http://dx.doi.org/10.3109/09546631003681078
Medical and Biotech [MESH] Definitions
Angioplasty, Laser
A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).
Laser Therapy, Low-level
Treatment using irradiation with LASER light of low power intensity so that the effects are not due to heat, as in LASER THERAPY. These non-thermal effects are thought to be mediated by a photochemical reaction that alters CELL MEMBRANE PERMEABILITY, leading to increased mRNA synthesis and CELL PROLIFERATION. Low-level laser therapy has been used for a wide variety of conditions, but most frequently for wound healing and pain control.
Warts
Benign epidermal proliferations or tumors; some are viral in origin.
Angioplasty, Balloon, Laser-assisted
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
Light Coagulation
The coagulation of tissue by an intense beam of light, including laser (LASER COAGULATION). In the eye it is used in the treatment of retinal detachments, retinal holes, aneurysms, hemorrhages, and malignant and benign neoplasms. (Dictionary of Visual Science, 3d ed)
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