Role of coffee in modulation of diabetes risk.
Summary of "Role of coffee in modulation of diabetes risk."
Coffee consumption has been associated with a lower risk of type 2 diabetes. This association does not depend on race, gender, geographic distribution of the study populations, or the type of coffee consumed (i.e., caffeinated or decaffeinated). This review discusses the strength of this relationship, examines the possibility that the pattern of coffee consumption could influence the association, and evaluates the possible relationship between coffee consumption and other risk factors associated with diabetes. Particular attention is paid to the identification, on the basis of the scientific evidence, of the possible mechanisms by which coffee components might affect diabetes development, especially in light of the paradoxical effect of caffeine on glucose metabolism. In addition to the role of coffee in reducing the risk of developing type 2 diabetes, the possible role of coffee in the course of the illness is explored. Finally, the possibility that coffee can also affect the risk of other forms of diabetes (e.g., type 1 diabetes and gestational diabetes) is examined.
Affiliation
The National Research Institute on Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Journal Details
This article was published in the following journal.
Name: Nutrition reviews
ISSN: 1753-4887
Pages: 207-17
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22458694
- DOI: http://dx.doi.org/10.1111/j.1753-4887.2012.00470.x
Medical and Biotech [MESH] Definitions
Prediabetic State
The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).
Antigenic Modulation
Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.
Pedunculopontine Tegmental Nucleus
Dense collection of cells in the caudal pontomesencephalic tegmentum known to play a role in the functional organization of the BASAL GANGLIA and in the modulation of the thalamocortical neuronal system.
Polyuria
Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).
Risk Reduction Behavior
Reduction of high-risk choices and adoption of low-risk quantity and frequency alternatives.
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