Bile acids in Non-Alcoholic Steato-Hepatitis: inserting nuclear receptors into the circle.
Summary of "Bile acids in Non-Alcoholic Steato-Hepatitis: inserting nuclear receptors into the circle."
No Summary Available
Affiliation
Center for Nuclear Receptors and Cell Signaling, University of Houston, 3013 Cullen Blv, 77204 Houston, Texas; Department of Biosciences and Nutrition, Karolinska Institutet, Novum, S-141 86, Sweden. cgabbi@central.uh.edu.
Journal Details
This article was published in the following journal.
Name: Hepatology (Baltimore, Md.)
ISSN: 1527-3350
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22535668
- DOI: http://dx.doi.org/10.1002/hep.25812
Medical and Biotech [MESH] Definitions
Liver Diseases, Alcoholic
Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
Bile Acids And Salts
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
Hepatitis A Virus, Human
A strain of HEPATITIS A VIRUS which causes hepatitis in humans. The virus replicates in hepatocytes and is presumed to reach the intestine via the bile duct. Transmission occurs by the fecal-oral route.
Nuclear Receptor Co-repressor 2
A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.
Hepatitis, Viral, Human
INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).
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