The nucleocapsid of vesicular stomatitis virus.
Summary of "The nucleocapsid of vesicular stomatitis virus."
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus. A unique mechanism for viral RNA synthesis is derived from the structure of the nuleocapsid and its interactions with the viral RNA-dependent RNA polymerase.
Affiliation
Department of Microbiology, the University of Alabama at Birmingham, Birmingham, 35294, USA, mingluo@uab.edu.
Journal Details
This article was published in the following journal.
Name: Science China. Life sciences
ISSN: 1869-1889
Pages: 291-300
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22566085
- DOI: http://dx.doi.org/10.1007/s11427-012-4307-x
Medical and Biotech [MESH] Definitions
Vesicular Stomatitis
A viral disease caused by at least two distinct species (serotypes) in the VESICULOVIRUS genus: VESICULAR STOMATITIS INDIANA VIRUS and VESICULAR STOMATITIS NEW JERSEY VIRUS. It is characterized by vesicular eruptions on the ORAL MUCOSA in cattle, horses, pigs, and other animals. In humans, vesicular stomatitis causes an acute influenza-like illness.
Vesicular Stomatitis New Jersey Virus
A species of VESICULOVIRUS causing VESICULAR STOMATITIS primarily in cattle, horses, and pigs. It can be transmitted to humans where it causes influenza-like symptoms.
Vesiculovirus
A genus of the family RHABDOVIRIDAE that infects a wide range of vertebrates and invertebrates. The type species is VESICULAR STOMATITIS INDIANA VIRUS.
Swine Vesicular Disease
An enterovirus infection of swine clinically indistinguishable from FOOT-AND-MOUTH DISEASE, vesicular stomatitis, and VESICULAR EXANTHEMA OF SWINE. It is caused by a strain of HUMAN ENTEROVIRUS B.
Rhabdoviridae Infections
Virus diseases caused by RHABDOVIRIDAE. Important infections include RABIES; EPHEMERAL FEVER; and vesicular stomatitis.
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