Track topics on Twitter Track topics that are important to you
The efficacy of Cassia alata against cestode Hymenolepis diminuta was evaluated in our study. Worms were maintained between rat model and beetle. Air-dried leaves of C. alata were subjected to ethanol extraction. Different concentrations (10-80 mg/ml) of the extract were prepared in phosphate buffer saline and tested on the parasite in vitro. Parasites treated with C. alata showed a decrease in motility with an increase in concentrations and complete immobilization took lesser time compared to control. The paralyzed parasites were further processed for electron microscopic studies. Ultrastructural micrographs revealed swelling of the tegument and blebbing on the tegumental surface throughout the body accompanied with destruction of microtriches and changes such as shrinkage in the scolex region. Depletion of parenchyma cells and destruction in the connective tissues along with sparsely cytoplasmic cytons were also observed, and these observations are similar with worms treated with a known drug praziquantel. These results may suggest that the plant leaves could be considered for controlling helminth infection and can represent a step forward in the search for alternative anthelmintic drug.
Department of Zoology, Visva Bharati, Santiniketan, 731235, West Bengal, India.
This article was published in the following journal.
Name: Parasitology research
Quorum sensing (QS) has been shown to play a crucial role in the pathogenesis in many bacteria and attenuation of QS is one of the targets of antimicrobial therapy with particular interest in combatin...
Cotton linters were dissolved in aq. (8%LiOH+15% Urea) that was pre-cooled to -12.5°C. Using this solution cellulose gel films were prepared by regeneration method with ethyl alcohol as a coagulant. ...
In order to investigate possible foliar transfer of toxic heavy metals, concentrations of Cd, Pb, and Fe were measured in samples of: Cassia siamea leaves (a common tree) Cassia siamea foliar dust, ne...
This study evaluated the effects of Newbouldia laevis and Cassia abbreviata extracts on CYP450 enzyme activity. Recombinant CYP450 enzyme and fluorogenic substrates were used for evaluating inhibition...
With an intention to find more potent anti-parasite agents, four bromoalkane substituted coumarin derivatives (1-4) and twenty coumarin-imidazole hybrid derivatives were synthesized and screened for t...
Cheap and effective drugs called 'anthelmintics' are routinely administered to children in developing countries to eliminate infections by parasitic helminths. However, the effects of anth...
The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and...
Uremic pruritus remains one of the most frustrating and potentially disabling symptoms in patients with end stage renal disease. It affect up to 90 percent of patients with end stage renal...
Primary Objective: - To evaluate the clinical efficacy of Naturetti (jelly sugar free) - To test medication on subjects who suffer chronic functional constipation in 30 days ...
Primary Objective: To evaluate the clinical efficacy of Naturetti (capsules) , considering the following criteria: - Evacuation frequency during the treatment and follow-up peri...
A plant genus of the family FABACEAE. SENNA EXTRACT is obtained from members of this genus. Members contain ANTHRAQUINONES and have been an ingredient in laxatives (CATHARTICS). Many species of the CASSIA genus have been reclassified into this genus. This bush should not be confused with the Cassia tree (CINNAMOMUM).
Infection with tapeworms of the genus Hymenolepis.
A genus of small tapeworms of birds and mammals.
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
A plant genus of the family FABACEAE. Some species were reclassified from CASSIA and Senna.
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...