Traversing the genomic landscape of prostate cancer from diagnosis to death.
Summary of "Traversing the genomic landscape of prostate cancer from diagnosis to death."
The clinical spectrum of prostate cancer ranges from curable, local disease to widely metastatic, lethal cancer. Two new prostate cancer genome studies provide the first glimpse at both ends of this spectrum.
Affiliation
Human Oncology and Pathogenesis Program at the Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Journal Details
This article was published in the following journal.
Name: Nature genetics
ISSN: 1546-1718
Pages: 613-4
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22641202
- DOI: http://dx.doi.org/10.1038/ng.2301
Medical and Biotech [MESH] Definitions
Prostate-specific Antigen
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Fenretinide
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Ultrasound, High-intensity Focused, Transrectal
Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).
Prostatic Secretory Proteins
Proteins secreted by the prostate gland. The major secretory proteins from the human prostate gland include PROSTATE-SPECIFIC ANTIGEN, prostate-specific acid phosphatase, prostate-specific membrane antigen, and prostate-specific protein-94.
Prostatic Neoplasms
Tumors or cancer of the PROSTATE.
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