Mutation in the THPO gene is not associated with aplastic anaemia in Japanese children.
Summary of "Mutation in the THPO gene is not associated with aplastic anaemia in Japanese children."
No Summary Available
Affiliation
Department of Paediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Journal Details
This article was published in the following journal.
Name: British journal of haematology
ISSN: 1365-2141
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22686250
- DOI: http://dx.doi.org/10.1111/j.1365-2141.2012.09185.x
Medical and Biotech [MESH] Definitions
Suppression, Genetic
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
Encephalitis Virus, Murray Valley
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), found in Australia and New Guinea. It causes a fulminating viremia resembling Japanese encephalitis (ENCEPHALITIS, JAPANESE).
Encephalitis Virus, Japanese
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), which is the etiological agent of Japanese encephalitis found in Asia, southeast Asia, and the Indian subcontinent.
Japanese Encephalitis Vaccines
Vaccines or candidate vaccines used to prevent infection with Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE).
Encephalitis Viruses, Japanese
A subgroup of the genus FLAVIVIRUS which comprises a number of viral species that are the etiologic agents of human encephalitis in many different geographical regions. These include Japanese encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE), St. Louis encephalitis virus (ENCEPHALITIS VIRUS, ST. LOUIS), Murray Valley encephalitis virus (ENCEPHALITIS VIRUS, MURRAY VALLEY), and WEST NILE VIRUS.
PubMed Articles
Hereditary thrombocythemia (HT) has been described as a rare benign disorder caused by mutations in the thrombopoietin (THPO) or the c-Mpl receptor genes. Here we report two families with HT resulting...
Severe Aplastic Anaemia in Six Children after Non-A-E Hepatitis without Hepatic Failure.
Aplastic anaemia can coincide with non-A-E hepatitis. Treatment follows a standardised study protocol of the German Society of Paediatric Oncology and Haematology (GPOH). Patients receive immunosuppre...
Association between polymorphisms in PDCD1 gene and aplastic anemia in Chinese Han population.
Abstract Single nucleotide polymorphism (SNP) of programmed cell death 1 (PD-1) has been reported to associate with several autoimmune diseases including rheumatoid arthritis (RA), Graves' disease and...
Clinical Trials
The purpose of this study is to examine the effect of G-CSF on disease free survival and overall survival in aplastic anaemia patients who also receive ATG and Cyclosporin A.
To assess the tolerability and effectiveness of rabbit antithymocyte globulin (ATG, Thymoglobuline) with ciclosporin in the first line treatment of patients with acquired severe aplastic a...
A Novel Mutation of the Spectrin Gene
The purpose of this study is to find a gene or its mutation (an altered gene) that puts individuals at risk for developing HE or HPP.
Factor V Leiden Mutation and Implantation Failure
The purpose of this study is to determine whether inherited thrombophilias (tendency toward blood clotting) increase the risk of failure of the embryo to implant in IVF. The specific cond...
Validation of 70-gene MammaPrint Profile in Japanese Population
By using gene-expression profiling, Van't Veer and colleagues developed a 70-gene prognosis profile, MammaPrint, to identify breast cancer patients who are at low risk of developing distan...