Guillain-Barré syndrome.
Summary of "Guillain-Barré syndrome."
No Summary Available
Affiliation
Department of Medicine, National University of Singapore, Singapore. yuki.research@gmail.com
Journal Details
This article was published in the following journal.
Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 2294-304
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22694000
- DOI: http://dx.doi.org/10.1056/NEJMra1114525
Medical and Biotech [MESH] Definitions
Zimeldine
One of the SEROTONIN UPTAKE INHIBITORS formerly used for depression but was withdrawn worldwide in September 1983 because of the risk of GUILLAIN-BARRE SYNDROME associated with its use. (From Martindale, The Extra Pharmacopoeia, 29th ed, p385)
Miller Fisher Syndrome
A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)
Autoimmune Diseases Of The Nervous System
Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).
Nervous System Autoimmune Disease, Experimental
Experimental animal models for human AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM. They include GUILLAIN-BARRE SYNDROME (see NEURITIS, AUTOIMMUNE, EXPERIMENTAL); MYASTHENIA GRAVIS (see MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL); and MULTIPLE SCLEROSIS (see ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL).
Polyradiculoneuropathy
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.
PubMed Articles
Medical progress: guillain-barré syndrome.
Medical Progress: Guillain-Barré Syndrome Review Article, N Engl J Med 2012;366:2294-2304. In the Clinical Features section, in the fourth paragraph under Diagnosis, beginning "A lumbar puncture . ....
Ptosis as the Initial Presentation of Guillain-Barré Syndrome.
BACKGROUND: Guillain-Barré syndrome has been regarded as a spectrum of diseases with many variants. OBJECTIVE: To present a case in which, when the ocular muscles are affected in the beginning, it is...
To the Editor: We are concerned that Yuki and Hartung (June 14 issue),(1) in their otherwise comprehensive review of the Guillain-Barré syndrome, have overlooked the importance of public health effor...
To the Editor: We are concerned that Yuki and Hartung (June 14 issue),(1) in their otherwise comprehensive review of the Guillain-Barré syndrome, have overlooked the importance of public health effor...
To the Editor: We are concerned that Yuki and Hartung (June 14 issue),(1) in their otherwise comprehensive review of the Guillain-Barré syndrome, have overlooked the importance of public health effor...
Clinical Trials
Early Mechanical Ventilation for Guillain Barré Syndrome
The purpose of this study is to determine whether early mechanical ventilation can prevent hospital acquired pneumonia in adults with Guillain Barré Syndrome.
OBJECTIVES: I. Compare the efficacy of plasmapheresis and human immunoglobulin infusion in minimizing morbidity and augmenting the pace of recovery in children with Guillain-Barre syndro...
Safety Study of GBS Following Menactra Meningococcal Vaccination
We are conducting a large, record-based study to assess the risk of Guillain-Barré Syndrome (GBS), a serious demyelinating disease, following immunization with the tetravalent meningococc...
Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-Aminopyridine
In developed countries, Guillain-Barre Syndrome (GBS) is the most common cause of acute neuromuscular paralysis, afflicting about 5,000 persons annually in the United States. Over 20% of G...
RATIONALE: Donor lymphocytes that have been exposed to Epstein-Barr virus may be able to help the body kill cancers associated with this virus. PURPOSE: Phase I trial to study the effecti...
