Ectomesenchymal chondromyxoid tumor: histopathologic and immunohistochemical study of two cases without a chondroid component.
Summary of "Ectomesenchymal chondromyxoid tumor: histopathologic and immunohistochemical study of two cases without a chondroid component."
Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign neoplasm usually affecting the anterior dorsum of the tongue. Histopathologically, it is formed by spindle, round and/or polygonal cells embedded in a chondromyxoid matrix. Immunohistochemical positivity for vimentin, S-100 protein, glial fibrillary acid protein and neuron-specific enolase are helpful to confirm the diagnosis. There are 42 cases of ECT of the tongue reported in the English language literature, three of them showing no chondroid matrix. We describe two additional cases of ECT lacking the chondroid component, exhibiting areas of reticulated myxoid and cellular pattern. Considering the microscopical features, ECT can be classified in classic and 'chondroid-free' variants, the latter including the reticulated myxoid and cellular patterns. It is important to consider that the cellular ECT usually exhibits predominance of an infiltrative atypical cellular component that may mimic a malignant tumor. Palma Guzmán JM, de Andrade BAB, Rizo VHT, Romañach MJ, León JE, de Almeida OP. Ectomesenchymal chondromyxoid tumor: histopathologic and immunohistochemical study of two cases without a chondroid component.
Oral Pathology Section, Dentistry School, Benemérita Universidad Autónoma de Puebla, Puebla, México Oral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
This article was published in the following journal.
Name: Journal of cutaneous pathology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22708841
- DOI: http://dx.doi.org/10.1111/j.1600-0560.2012.01910.x
Medical and Biotech [MESH] Definitions
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Granulosa Cell Tumor
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Ectomesenchymal chondromyxoid tumor of the anterior tongue is a rare entity. To date, 37 cases have been reported in the literature. We present the case of a 52-year-old male patient with an ectomesen...
Ectomesenchymal chondromyxoid tumor is a rare tumor seen in the anterior dorsal aspect of the tongue. Diagnosis of this lesion without a prediagnosis clinically is made only with histopathological fin...
An ectomesenchymal chondromyxoid tumor (ECMT) is a rare neoplasm that exclusively occurs in the anterior dorsum of the tongue. The tumor consists of small round to fusiform or spindle cells with myxoi...
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