What's in a drop? Optimizing strategies for administration of drugs in pediatrics.
Summary of "What's in a drop? Optimizing strategies for administration of drugs in pediatrics."
Accurate administration of drugs is an essential part of pharmacotherapy in children. Small differences in the amount of drugs administered, might evoke different clinical effects. This is especially of concern in drugs with a narrow therapeutic index. Guided by a case that was observed in pediatrics, some practical recommendations for the administration of oral drops in children are described.
Department of Pharmacy, Ghent University Hospital, -1 K12, De Pintelaan 185, 9000, Ghent, Belgium, firstname.lastname@example.org.
This article was published in the following journal.
Name: International journal of clinical pharmacy
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22777318
- DOI: http://dx.doi.org/10.1007/s11096-012-9670-y
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Medical and Biotech [MESH] Definitions
The administration of therapeutic agents drop by drop, as eye drops, ear drops, or nose drops. It is also administered into a body space or cavity through a catheter. It differs from irrigation in that the irrigate is removed within minutes, but the instillate is left in place.
Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
The administration of drugs through the nasal passage.
The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.
Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.