Painless jaundice: a clear case?
Summary of "Painless jaundice: a clear case?"
A 44-year-old male patient presented with suddenly occurring first time painless jaundice. The patient history included whitish colored stools but no fever or weight loss. Imaging diagnostics and blood analysis revealed a strong suspicion of pancreatic disease. Histological examination showed dense plasma and lymphocellular infiltration and areas of fibrosis of the pancreatic parenchyma and confirmed the diagnosis of autoimmune pancreatitis which was successfully treated with immunosuppressive drugs.
Universitätsklinikum Frankfurt a.M., Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland, Thorsten.Burkhard@kgu.de.
This article was published in the following journal.
Name: Der Radiologe
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22777307
- DOI: http://dx.doi.org/10.1007/s00117-012-2352-x
Medical and Biotech [MESH] Definitions
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
JAUNDICE, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.
Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
Accumulation of BILIRUBIN, a breakdown product of HEME PROTEINS, in the BLOOD during the first weeks of life. This may lead to NEONATAL JAUNDICE. The excess bilirubin may exist in the unconjugated (indirect) or the conjugated (direct) form. The condition may be self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) or pathological with toxic levels of bilirubin.
Adenocarcinoma, Clear Cell
An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
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