Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity.

12:30 EDT 31st October 2014 | BioPortfolio

Summary of "Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity."

Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.

Affiliation

Department of Chemistry, Center for Electro-Photo Behaviors in Advanced Molecular Systems, POSTECH, San 31, Hyoja-dong, Pohang, 790-784, Republic of Korea. ahn@postech.ac.kr.

Journal Details

This article was published in the following journal.

Name: Chemical communications (Cambridge, England)
ISSN: 1364-548X
Pages: 6833-5

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