Depression and coronary heart disease: Apprehending the elusive black dog.
Summary of "Depression and coronary heart disease: Apprehending the elusive black dog."
Depression is the third leading cause of disease burden worldwide and is predicted to be the leading cause by 2030. Importantly, depression has been identified as an independent risk factor for coronary heart disease (CHD) and both share significant physiological overlap. Identification of depression is complex. Consequently, accurate diagnosis of comorbid depression and CHD is challenging and requires a move toward an interdisciplinary engagement of knowledge transfer. A concerted effort is required utilising translational research to better identify depression in the CHD population. This approach is not meant to categorise patients, rather it is aimed at progressing toward an improved prognosis. Further, this approach should provide health professionals with the confidence to apply the term depression and define its meaning in a more precise and consistent manner.
This article was published in the following journal.
Name: International journal of cardiology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22261693
- DOI: http://dx.doi.org/10.1016/j.ijcard.2011.12.088
Medical and Biotech [MESH] Definitions
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Coronary Artery Bypass, Off-pump
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
Coronary Artery Bypass
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
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