Quality of Life in Breast Cancer Patients with Bisphosphonate-related Osteonecrosis of the Jaws and Patients with Head and Neck Cancer: A Comparative Study Using the EORTC QLQ-C30 and QLQ-HN35 Questionnaires.
Summary of "Quality of Life in Breast Cancer Patients with Bisphosphonate-related Osteonecrosis of the Jaws and Patients with Head and Neck Cancer: A Comparative Study Using the EORTC QLQ-C30 and QLQ-HN35 Questionnaires."
Background/Aim: This exploratory study aimed at examining the diagnostic utility, validity and reliability of already established quality of life (QoL) measures in cancer patients with osteonecrosis of the jaws (ONJ).
Affiliation
DDS, MSc, 3 Papazoli St, Thessaloniki, 546 30, Greece. Mob: +30 6947566727, akyrgidi@gmail.com.
Journal Details
This article was published in the following journal.
Name: Anticancer research
ISSN: 1791-7530
Pages: 3527-34
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22843941
- DOI: http://dx.doi.org/
Medical and Biotech [MESH] Definitions
Mucin-1
Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
Inflammatory Breast Neoplasms
Metastatic breast cancer characterized by EDEMA and ERYTHEMA of the affected breast due to LYMPHATIC METASTASIS and eventual obstruction of LYMPHATIC VESSELS by the cancer cells.
Brca1 Protein
The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)
Carcinoma, Lobular
A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)
Breast Neoplasms
Tumors or cancer of the human BREAST.
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