Advertisement

Still making the case against prehospital intubation: A rat hemorrhagic shock model.

21:39 EDT 18th May 2013 | BioPortfolio

Summary of "Still making the case against prehospital intubation: A rat hemorrhagic shock model."

Prehospital intubation does not appear to result in a survival advantage for patients experiencing penetrating trauma; yet, there is still resistance to the practice of "scoop and run" to speed access to advanced care. An animal model was used to determine whether intubation provides a survival advantage during potentially lethal hemorrhage.

Affiliation

From the Department of Surgery (S.T., S.J., R.E.M., L.O.S., A.P., T.A.S., A.J.G.), Temple University Hospital; and Cardiovascular Research Center (S.T., J.M.D., S.R.H.), and Biostatistics Consulting Center (J.P.G.), Temple University School of Medicine (G

Journal Details

This article was published in the following journal.

Name: The journal of trauma and acute care surgery
ISSN: 2163-0763
Pages: 332-7

Links

Medical and Biotech [MESH] Definitions

Dengue Hemorrhagic Fever

A distinct and virulent form of DENGUE characterized by thrombocytopenia and hemoconcentration (grades I and II) and distinguished by a positive tourniquet test. When accompanied by circulatory failure and shock (grades III and IV), it is called dengue shock syndrome. (From Dorland, 28th ed)

Exsanguination

Rapid and extreme blood loss leading to HEMORRHAGIC SHOCK.

Shock, Hemorrhagic

Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.

Hemorrhagic Fevers, Viral

A group of viral diseases of diverse etiology but having many similar clinical characteristics; increased capillary permeability, leukopenia, and thrombocytopenia are common to all. Hemorrhagic fevers are characterized by sudden onset, fever, headache, generalized myalgia, backache, conjunctivitis, and severe prostration, followed by various hemorrhagic symptoms. Hemorrhagic fever with kidney involvement is HEMORRHAGIC FEVER WITH RENAL SYNDROME.

Hsp40 Heat-shock Proteins

A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.

PubMed Articles [ 10333 Associated PubMed Articles listed on BioPortfolio]

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.

Hemorrhagic shock is known to disrupt the gut barrier leading to end-organ dysfunction. The vagus nerve can inhibit detrimental immune responses that contribute to organ damage in hemorrhagic shock. T...

Fish Oil improves Hemodynamic Stabilization and Inflammation after Resuscitation in a Rat Model of Hemorrhagic Shock.

ABSTRACT: BACKGROUND: Hemorrhagic shock followed by resuscitation stimulates an inflammatory response. This study tests the hypothesis that treatment with fish oil will attenuate inflammatory respons...

Nitric oxide modulates biphasic changes of isolated lymphatic contraction in hemorrhagic shock rats.

The aim of the present study was to investigate the changes of lymphatic contraction after hemorrhagic shock in vitro and the underlying role of nitric oxide (NO). Rat thoracic duct segments were isol...

Small Volume 7.5% NaCl With 6% Dextran-70 or 6% and 10% Hetastarch Are Associated With Arrhythmias and Death After 60 Minutes of Severe Hemorrhagic Shock in the Rat In Vivo.

BACKGROUND:: Hypertonic saline solutions in combination with colloids may have some applications in critically ill patients. Our aim was to examine the effects of small volumes (0.7-1 mL/kg intravenou...

Laryngeal tube as airway rescue device from prehospital tracheostomy: a case report.

Airway management is a priority for the critically ill patient. The insertion of a cuffed tracheal tube is the best practice to obtain an airway control; however, it is associated with many practical...

Clinical Trials [ 1342 Associated Clinical Trials listed on BioPortfolio]

Safety and Efficacy of PolyHeme(R) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-Hospital Setting

This study is designed to assess the survival benefit of administering PolyHeme to severely injured trauma patients in hemorrhagic shock beginning in the prehospital setting, where blood...

Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans

Hemorrhagic shock is typically identified by the degree of hypotension that develops as a result of blood loss and remains a leading cause of death on the battlefield as well as worldwide....

Vasopressin in Traumatic Hemorrhagic Shock Study

The purpose of the present trial is therefore to assess effects of arginine vasopressin vs. saline placebo on hospital admission rate (primary end point), as well as hemodynamic variables,...

Resuscitative Endocrinology: Single-dose Clinical Uses for Estrogen - Traumatic Hemorrhagic Shock (RESCUE - Shock)

Annually in the United States, approximately 30 million people require treatment for traumatic injuries in emergency departments. Two million of these patients require hospitalization, wi...

Rapid Sequence Intubation With Rocuronium-Sugammadex Compared With Succinylcholine

Rapid sequence intubation is used, when there is an elevated risk of aspiration to the lungs of stomach content. It is typically used in acute settings that require acute surgery or in pre...

Search BioPortfolio:
Advertisement
Advertisement