Visual recovery after corneal crosslinking for keratoconus: a 1-year follow-up study.

01:13 EST 29th November 2014 | BioPortfolio

Summary of "Visual recovery after corneal crosslinking for keratoconus: a 1-year follow-up study."


PURPOSE:
To evaluate visual recovery and intraocular straylight in keratoconus patients 3 months and 1 year after corneal crosslinking (CXL) PATIENTS AND
METHODS:
Thirty-three eyes of 28 consecutive patients with mild to moderate keratoconus were included. The following were assessed at baseline, 3 months and 1 year after
CXL:
corrected distance visual acuity (CDVA), intraocular straylight, spherical equivalent (SE), keratometry (Kmax and K min (Diopters D and axis), the regularity index and pachymetry. Changes from baseline were calculated using mixed linear regression models.
RESULTS:
The CDVA remained unchanged 3 months after CXL (-0.003 (95 %
CI:
-0.038 to 0.044); p = 0.880) and improved after 1 year (-0.042 (95 %
CI:
-0.078 to -0.007; p = 0.021)). The mean straylight value increased significantly by 0.27 (95 %
CI:
0.18 to 0.35; p < 0.001) 3 months after CX and normalized to preoperative values after 1 year (0.06 (95 %
CI:
-0.03 to 0.14; p = 0.215)). SE improved from the mean preoperative value of -2.61 D (95 %
CI:
-3.83 to -1.39) by 1.95 (95 %
CI:
1.03 to 2.86; p < 0.001) at 3 months and remained stable at the 1-year follow-up visit (2.17 (95 %
CI:
1.21 to 3.12; p < 0.001)). Parameters of of keratometry changed only minimally. The regularity index remained almost unchanged at 3 months (2.45 (95 %
CI:
-4.97 to 9.88; p = 0.503)) and decreased by 6.97 (95 %
CI:
-14.08 to 0.14; p = 0.054). Pachymetry decreased by 44.0 μm (95 %
CI:
56.1 to 31.9; p < 0.001) at 3 months and almost returned to preoperative values at 12 months (-11.3 μm (95 %
CI:
-27.9 to 5.3; p = 0.175)).
CONCLUSIONS:
In accordance with the decrease in CDVA and patients' complaints of disability due to glare, intraocular straylight increased 3 months after surgery. One year after CXL, there was an increase in CDVA due to an improved SE and regularity index, and intraocular straylight had normalized.

Affiliation

Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Ivo.Guber@ksw.ch.

Journal Details

This article was published in the following journal.

Name: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Opht
ISSN: 1435-702X
Pages:

Links

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