The Hypertension in the Very Elderly Trial - Latest Data.
Summary of "The Hypertension in the Very Elderly Trial - Latest Data."
Early trials in the field of hypertension focused on adults in their fifties and sixties. However, with the passage of time, a progressive effort has been made to expand the evidence base for treatment in older adults. 2008 saw publication of data from the Hypertension in the Very Elderly Trial - this demonstrated significant mortality and morbidity benefits from antihypertensive therapy in octogenarians. More recently, additional data from this cohort has been published suggesting that appropriate anti-hypertensive therapy may lead to a reduction in incident cognitive impairment and fractures, whilst a one year open label extension of the main study confirmed many of the original trial findings. This review provides an overview of the Hypertension in the Very Elderly Trial whilst also discursively evaluating the latest data.
Clinical Pharmacology & Therapeutics, King's Health Partners, King's College Hospital, Denmark Hill, London. firstname.lastname@example.org.
This article was published in the following journal.
Name: British journal of clinical pharmacology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22897422
- DOI: http://dx.doi.org/10.1111/j.1365-2125.2012.04427.x
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