Correlation of photographic images from the Leeds revised acne grading system with a six-category global acne severity scale.
Summary of "Correlation of photographic images from the Leeds revised acne grading system with a six-category global acne severity scale."
Backgroundâ€‚ Few global acne grading systems include individualized assessments of chest and back as well as face. The Leeds revised acne grading system is based on photographic images while the Comprehensive Acne Severity Scale (CASS) is based on textual descriptions. There exists an unmet need for a global scale based on both text and photos. Purposeâ€‚ Our objective was to evaluate the correspondence of severity grades from descriptive text (CASS grades) for each Leeds image. Methodsâ€‚ Twenty-three dermatologists independently graded 56 photos of face, chest and back of varying acne severity using CASS. Photographs were randomly presented from the The Leeds revised acne grading system (nâ€ƒ=â€ƒ31) and from acne patients of the corresponding author (nâ€ƒ=â€ƒ25). For each Leeds photo, rater responses for CASS grades were transformed into median, coefficient of variation and percentiles. Resultsâ€‚ High rater agreement (â‰¥75%) was observed for Leeds facial inflammatory 2 (CASS 3), 4 (CASS 4), 6 (CASS 4), 9-12 (all CASS 5); Leeds facial comedonal A (CASS 2); Leeds chest 7 and 8 (both CASS 5); and Leeds back 7 and 8 (both CASS 5). Lowest coefficients of variance were observed in Leeds facial inflammatory 4, 9, 10, 11; Leeds facial comedonal A; Leeds chest 7 and 8; and Leeds back 8. Conclusions Leeds photos, by inadequately portraying facial acne grades 1 (almost clear) and 2 (mild) and back and chest grades 1-4 (almost clear to severe), cannot accurately represent the spectrum of severity in a six-category global acne scale. Accordingly, there is a current need for images that correspond to a categorical acne scale.
University of Western Ontario and Windsor Clinical Research Inc., Deptartment of Mathematics and Statistics, University of Windsor, Windsor, Ontario Windsor Program, Schulich School of Medicine and Dentistry, University of Western Ontario, Ontario, Canada
This article was published in the following journal.
Name: Journal of the European Academy of Dermatology and Venereology : JEADV
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22924863
- DOI: http://dx.doi.org/10.1111/j.1468-3083.2012.04692.x
Medical and Biotech [MESH] Definitions
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
The recording of images in three-dimensional form on a photographic film by exposing it to a laser beam reflected from the object under study.
Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575)
Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).
Combination or superimposition of two images for demonstrating differences between them (e.g., radiograph with contrast vs. one without, radionuclide images using different radionuclides, radiograph vs. radionuclide image) and in the preparation of audiovisual materials (e.g., offsetting identical images, coloring of vessels in angiograms).
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