Pathological findings and pulmonary dysfunction after acute respiratory distress syndrome for 5 years.

12:59 EDT 2nd September 2015 | BioPortfolio

Summary of "Pathological findings and pulmonary dysfunction after acute respiratory distress syndrome for 5 years."

We report the pathological findings of the lung after acute respiratory distress syndrome (ARDS), and pulmonary function tests during five years of follow-up. A 39-year-old woman, treated for acute myelogenous leukemia, developed ARDS. She recovered from ARDS but suffered from pulmonary aspergillosis. Her aspergilloma was removed surgically. Her lung function tests and diffusing capacity of the lung for carbon monoxide (DL(CO)) improved but diffusion impairment remained five years after recovery. Pathological examination of the resected material showed sclerosis in lobular septa and scattered fibrosis in alveolar ducts except for the aspergillosis. These fibrotic changes may be causally associated with her loss of DL(CO).


Department of Pulmonary Medicine, Jichi Medical University Saitama Medical Center.

Journal Details

This article was published in the following journal.

Name: Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Pages: 1599-604


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Medical and Biotech [MESH] Definitions

A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).

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