Environmental and occupational exposure of metals and their role in male reproductive functions.
Summary of "Environmental and occupational exposure of metals and their role in male reproductive functions."
This review summarizes the effects of more than 20 metals that, research has indicated, may influence male reproductive health. Though males lack an apparent, easily measurable reproductive cycle, progress has been made in evaluating tests to identify chemical hazards and estimate reproductive health risks. Some agents discussed in this review are well known to have potential toxic effects on the male reproductive system, whereas some are not so well established in toxicology. This review attempts to cover most of the known toxicants and their effects on male fertility. The literature suggests a need for further research in those chemicals that are reactive and capable of covalent interactions in biological systems, as well as those defined as mutagens and/or carcinogens, to cause aneuploidy or other chromosomal aberrations, affect sperm motility in vitro, share hormonal activity or affect hormone action, and those that act directly or indirectly to affect the hypothalamo-pituitary-gonadal axis.
Affiliation
Department of Physiology, Vidyasagar College for Women, University of Calcutta , Kolkata, West Bengal , India.
Journal Details
This article was published in the following journal.
Name: Drug and chemical toxicology
ISSN: 1525-6014
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22947100
- DOI: http://dx.doi.org/10.3109/01480545.2012.710631
Medical and Biotech [MESH] Definitions
Paternal Exposure
Exposure of the male parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring.
Environmental Exposure
The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.
Tuberculosis, Male Genital
MYCOBACTERIUM infections of the male reproductive tract (GENITALIA, MALE).
Genital Diseases, Male
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
Male Urogenital Diseases
Pathological processes of the male URINARY TRACT and the reproductive system (GENITALIA, MALE).
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