Pushing the ir-catalyzed C-h polyborylation of aromatic compounds to maximum capacity by exploiting reversibility.
Summary of "Pushing the ir-catalyzed C-h polyborylation of aromatic compounds to maximum capacity by exploiting reversibility."
Small amounts of base (e.g., 10% potassium t-butoxide or sodium methoxide) have been found to promote equilibration of the kinetically favored products from Ir-catalyzed C-H polyborylations of aromatic compounds. In the presence of excess borylating agent, bis(pinacolato)diborane (B(2)pin(2)), repetitive deborylation/reborylations reposition the Bpin substituents until a pattern that accommodates the maximum number of Bpin substituents is achieved. A high-yield, one-step synthesis of 1,3,5,7,9-pentakis(Bpin)corannulene is reported that illustrates this useful extension of the Ir-catalyzed borylation reaction.
Merkert Chemistry Center, Boston College , Chestnut Hill, Massachusetts 02467-3860, United States.
This article was published in the following journal.
Name: Journal of the American Chemical Society
Medical and Biotech [MESH] Definitions
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
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Measurement of the maximum rate of airflow attained during a FORCED VITAL CAPACITY determination. Common abbreviations are PEFR and PFR.
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