Highly porous titanium scaffolds for orthopaedic applications.

06:00 EDT 7th August 2010 | BioPortfolio

Summary of "Highly porous titanium scaffolds for orthopaedic applications."

For many years, the solid metals and their alloys have been widely used for fabrication of the implants replacing hard human tissues or their functions. To improve fixation of solid implants to the surrounding bone tissues, the materials with porous structures have been introduced. By tissue ingrowing into a porous structure of metallic implant, the bonding between the implant and the bone has been obtained. Substantial pore interconnectivity, in metallic implants, allows extensive body fluid transport through the porous implant. This can provoke bone tissue ingrowth, consequently, leading to the development of highly porous metallic implants, which could be used as scaffolds in bone tissue engineering. The goal of this study was to develop and then investigate properties of highly porous titanium structures received from powder metallurgy process. The properties of porous titanium samples, such as microstructure, porosity, Young's modulus, strength, together with permeability and corrosion resistance were investigated. Porous titanium scaffolds with nonhomogeneous distribution of interconnected pores with pore size in the range up to 600 mum in diameter and a total porosity in the range up to 75% were developed. The relatively high permeability was observed for samples with highest values of porosity. Comparing to cast titanium, the porous titanium was low resistant to corrosion. The mechanical parameters of the investigated samples were similar to those for cancellous bone. The development of high-porous titanium material shows high potential to be modern material for creating a 3D structure for bone regeneration and implant fixation. (c) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part
Appl Biomater, 2010.


Division of Materials Design, Faculty of Materials Science and Engineering, Warsaw University of Technology, 02-507 Warsaw, Poland.

Journal Details

This article was published in the following journal.

Name: Journal of biomedical materials research. Part B, Applied biomaterials
ISSN: 1552-4981


DeepDyve research library

PubMed Articles [14324 Associated PubMed Articles listed on BioPortfolio]

Quantitative stereological analysis of the highly porous hydroxyapatite scaffolds using X-ray CM and SEM.

Material properties of the scaffolds as well as their microstructure are vital in determining in vivo cellular response. Three-dimensional (3D), highly porous scaffolds are used in tissue engineering ...

Mechanical properties and biocompatibility of porous titanium scaffolds for bone tissue engineering.

Synthetic scaffolds are a highly promising new approach to replace both autografts and allografts to repair and remodel damaged bone tissue. Biocompatible porous titanium scaffold was manufactured thr...

Midterm Outcomes of Revision Total Hip Arthroplasty With the Use of a Multihole Highly-Porous Titanium Shell.

We are reporting on the minimum 5-year outcomes of patients who underwent revision total hip arthroplasty (THA) using a specific highly-porous titanium shell. We assessed (1) aseptic and all-cause sur...

3D printed porous ceramic scaffolds for bone tissue engineering: a review.

This study summarizes the recent research status and development of three-dimensional (3D)-printed porous ceramic scaffolds in bone tissue engineering. Recent literature on 3D-printed porous ceramic s...

Porous titanium scaffolds with self-assembled micro/nano hierarchical structure for dual functions of bone regeneration and anti-infection.

Porous titanium (Ti) scaffolds are widely used for bone repair because of their good biocompatibility, mechanical properties and corrosion resistance. However, pristine Ti scaffolds are bioinert and u...

Clinical Trials [1285 Associated Clinical Trials listed on BioPortfolio]

Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis

This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a...

Slow-release Tb4 Collagen and Chitosan Porous Sponge Scaffolds Skin Substitute Treatment is Difficult to Heal Wounds

Evaluation of slow-release Tb4 collagen and chitosan porous sponge scaffolds skin substitutes the effectiveness of clinical trials for the treatment of difficult to heal wounds and securit...

Implantation of Porous Titanium Prosthesis in Laryngeal Surgery

This study evaluates a medialization implant to treat vocal cord paralysis, to permit it to adjust the quality of the voice under local or general anesthesia. The aim is to restore phonati...

A Study to Treat Patients With Edentulous Mandibles With Two Straumann 3.3mm Diameter Bone Level Implants

The purpose of this study is to assess the change of crestal bone level at the Titanium Zirconium (TiZr) compared to Titanium (grade IV) implant between surgery and 6, 12, 24, and 36 month...

Coronary Microcirculatory and Bioresorbable Vascular Scaffolds

Angina and heart attacks are caused by narrowings in the coronary arteries (blood vessels) supplying the heart. These narrowings can be opened using a balloon and stent (angioplasty). Trad...

Medical and Biotech [MESH] Definitions

Heparin derivatives. The term has also been used more loosely to include naturally occurring and synthetic highly-sulphated polysaccharides of similar structure. Heparinoid preparations have been used for a wide range of applications including as anticoagulants and anti-inflammatories and they have been claimed to have hypolipidemic properties. (From Martindale, The Extra Pharmacopoeia, 30th, p232)

A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From Merck Index, 11th ed)

Polymer of polytetrafluoroethylene and carbon filaments; porous biocompatible material used in orofacial and middle ear reconstruction and as coating for metal implants.

The application of scientific knowledge or technology to the field of radiology. The applications center mostly around x-ray or radioisotopes for diagnostic and therapeutic purposes but the technological applications of any radiation or radiologic procedure is within the scope of radiologic technology.

Union of the fragments of a fractured bone in a faulty or abnormal position. If two bones parallel to one another unite by osseous tissue, the result is a crossunion. (From Manual of Orthopaedic Terminology, 4th ed)

Quick Search

DeepDyve research library

Relevant Topics

Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...

Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...

Searches Linking to this Article