Track topics on Twitter Track topics that are important to you
For many years, the solid metals and their alloys have been widely used for fabrication of the implants replacing hard human tissues or their functions. To improve fixation of solid implants to the surrounding bone tissues, the materials with porous structures have been introduced. By tissue ingrowing into a porous structure of metallic implant, the bonding between the implant and the bone has been obtained. Substantial pore interconnectivity, in metallic implants, allows extensive body fluid transport through the porous implant. This can provoke bone tissue ingrowth, consequently, leading to the development of highly porous metallic implants, which could be used as scaffolds in bone tissue engineering. The goal of this study was to develop and then investigate properties of highly porous titanium structures received from powder metallurgy process. The properties of porous titanium samples, such as microstructure, porosity, Young's modulus, strength, together with permeability and corrosion resistance were investigated. Porous titanium scaffolds with nonhomogeneous distribution of interconnected pores with pore size in the range up to 600 mum in diameter and a total porosity in the range up to 75% were developed. The relatively high permeability was observed for samples with highest values of porosity. Comparing to cast titanium, the porous titanium was low resistant to corrosion. The mechanical parameters of the investigated samples were similar to those for cancellous bone. The development of high-porous titanium material shows high potential to be modern material for creating a 3D structure for bone regeneration and implant fixation. (c) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part
Appl Biomater, 2010.
Division of Materials Design, Faculty of Materials Science and Engineering, Warsaw University of Technology, 02-507 Warsaw, Poland.
This article was published in the following journal.
Name: Journal of biomedical materials research. Part B, Applied biomaterials
Enhanced angiogenesis and osteogenesis in critical bone defects by the controlled release of BMP-2 and VEGF: implantation of electron beam melting-fabricated porous Ti6Al4V scaffolds incorporating growth factor-doped fibrin glue.
Electron beam melting (EBM)-fabricated porous titanium implants possessing low elastic moduli and tailored structures are promising biomaterials for orthopedic applications. However, the bio-inert nat...
Porous scaffolds of Ti-6Al-4V were produced by mixing of this alloy with different amount of magnesium (Mg) powders. The mixtures were compacted in steel die by applying uniaxial pressure of 500MPa be...
The use of Polyetheretherketone (PEEK) composites in the trauma plating system, total replacement implants, and tissue scaffolds has found great interest among researchers. In recent years (2008 after...
Regeneration of load-bearing segmental bone defects is a major challenge in trauma and orthopaedic surgery. The ideal bone graft substitute is a biomaterial that provides immediate mechanical stabilit...
For the first time, forward osmosis (FO) was performed using a porous membrane with an ultrafiltration (UF)-like rejection layer and its feasibility for high performance FO filtration was demonstrated...
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a...
This study evaluates a medialization implant to treat vocal cord paralysis, to permit it to adjust the quality of the voice under local or general anesthesia. The aim is to restore phonati...
The purpose of this study is to assess the change of crestal bone level at the Titanium Zirconium (TiZr) compared to Titanium (grade IV) implant between surgery and 6, 12, 24, and 36 month...
Primary objective : To evaluate the quality of fractures setting and osteotomy of the facial massif osteosynthesised with resorbable device PLLA/PGA compared with usual Titanium plates. ...
Titanium elastic nails in the pediatric femoral fractures: A prospective randomized clinical trial of eliminating nail protrusion to decrease soft tissue complications
The application of scientific knowledge or technology to the field of radiology. The applications center mostly around x-ray or radioisotopes for diagnostic and therapeutic purposes but the technological applications of any radiation or radiologic procedure is within the scope of radiologic technology.
Heparin derivatives. The term has also been used more loosely to include naturally occurring and synthetic highly-sulphated polysaccharides of similar structure. Heparinoid preparations have been used for a wide range of applications including as anticoagulants and anti-inflammatories and they have been claimed to have hypolipidemic properties. (From Martindale, The Extra Pharmacopoeia, 30th, p232)
A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From Merck Index, 11th ed)
Polymer of polytetrafluoroethylene and carbon filaments; porous biocompatible material used in orofacial and middle ear reconstruction and as coating for metal implants.
Union of the fragments of a fractured bone in a faulty or abnormal position. If two bones parallel to one another unite by osseous tissue, the result is a crossunion. (From Manual of Orthopaedic Terminology, 4th ed)
Latest News Clinical Trials Research Drugs Reports Corporate
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...
Latest News Clinical Trials Research Drugs Reports Corporate
Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...