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Aim: The study aimed to assess, for the first time, the effectiveness of Interferential Therapy (IFT) in the treatment of slow-transit constipation in adults and its impact on the quality of life. Method: All consecutive patients with slow-transit constipation diagnosed by symptomology and a colonic transit time (CTT) of >100 hours (h) measured with radiopaque markers were included in this prospective study. IFT was performed for 1 hour per day over 3 months. Clinical improvement was based on the stool diary and the KESS and Cleveland Clinic Constipation scores. Quality of life was assessed with the GIQLI questionnaire. Results: Eleven patients with a median age of 51 years were included. At the end of the follow-up period, 7 (63.6%) had significantly improved after IFT with a median of 0.66 stools per week (IQR, 0.33-0.66) before treatment and 1.66 (IQR, 1.33-1.66) after (p=0.007). The KESS score rose from 30 (IQR, 27-33) before treatment to 19 (IQR, 17-26) after treatment (15-33) (p=0.005) and the Cleveland Clinic Constipation Score from 26 (IQR, 25-28) to 17 (IQR, 13-24) (p=0.005). The CTT improved from 103 (IQR, 101-113) to 98 (IQR, 94-107) (p=0.02) h. The GIQLI score improved from 60 (IQR, 57-63) to 95 (IQR, 68-100) (p=0.005). Conclusion: Interferential therapy is a new, non-invasive treatment for slow transit constipation. Further studies to confirm these results with longer follow-up are necessary. © 2012 The Authors Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.
Service de colo-proctologie, Clinique des cèdres, Cornebarrieu Service de gastroentérologie, CHU Nord, Marseille Interface de recherche translationnelle en neurogastroentérologie, CRN2M, UMR 7286, Aix-Marseille Université, Marseille Unité de recherch
This article was published in the following journal.
Name: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
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