Derivation of a finite element model of lingual deformation during swallowing from the mechanics of mesoscale myofiber tracts obtained by MRI.
Summary of "Derivation of a finite element model of lingual deformation during swallowing from the mechanics of mesoscale myofiber tracts obtained by MRI."
To demonstrate the relationship between lingual myoarchitecture and mechanics during swallowing, we performed a finite element (FE) simulation of lingual deformation employing mesh aligned with the vector coordinates of myofiber tracts obtained by diffusion tensor imaging (DTI) with tractography in humans. Material properties of individual elements were depicted in terms of Hill's 3-component phenomenological model, assuming that the FE mesh was composed of anisotropic muscle and isotropic connective tissue, FE element structure of imaged tissue was elastically constrained from the superior and inferior directions, and passive bolus effects were negligible. Myofiber tract activation was simulated over 500 ms in 1 ms steps following lingual tip association with the hard palate and incorporated specifically the accommodative and propulsive phases of the swallow. Examining the displacement field, active and passive muscle stress, elemental stretch and strain rate relative to changes of global shape, we demonstrate that lingual reconfiguration during these swallow phases is characterized by (in sequence) 1) lingual tip elevation and shortening in the anterior-posterior direction, 2) inferior displacement related to hyoglossus contraction at its inferior-most position, and 3) dominant clockwise rotation related to regional contraction of the genioglossus and contraction of the hyoglossus following anterior displacement. These simulations demonstrate that lingual deformation during the indicated phases of swallowing requires temporally patterned activation of intrinsic and extrinsic muscles, and delineate a method to ascertain the mechanics of normal and pathological swallowing.
Affiliation
1Harvard School of Public Health.
Journal Details
This article was published in the following journal.
Name: Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20689096
- DOI: http://dx.doi.org/10.1152/japplphysiol.00493.2010
Medical and Biotech [MESH] Definitions
Finite Element Analysis
A computer based method of simulating or analyzing the behavior of structures or components.
Lingual Goiter
Pathological enlargement of the LINGUAL THYROID, ectopic thyroid tissue at the base of the TONGUE. It may cause upper AIRWAY OBSTRUCTION; DYSPHAGIA; or HYPOTHYROIDISM symptoms.
Models, Statistical
Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.
Lingual Nerve
A sensory branch of the MANDIBULAR NERVE, which is part of the trigeminal (5th cranial) nerve. The lingual nerve carries general afferent fibers from the anterior two-thirds of the tongue, the floor of the mouth, and the mandibular gingivae.
Lingual Thyroid
A condition characterized by the presence of rudimentary THYROID tissue at the base of the TONGUE. It is due to failed embryonic development and migration of thyroid tissue to its normal location. The lingual thyroid usually cannot maintain adequate hormone production thereby resulting in HYPOTHYROIDISM.
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