Degradation of the Alternaria Mycotoxins Alternariol, Alternariol Monomethyl Ether, and Altenuene upon Bread Baking.
Summary of "Degradation of the Alternaria Mycotoxins Alternariol, Alternariol Monomethyl Ether, and Altenuene upon Bread Baking."
The stability of the Alternaria mycotoxins alternariol, alternariol monomethyl ether, and altenuene upon bread baking was investigated by model experiments using a spiked wholemeal wheat flour matrix. For alternariol and alternariol monomethyl ether, but not for altenuene, degradation products, formed through a sequence of hydrolysis and decarboxylation, could be identified in pilot studies. The simultaneous quantification of alternariol, alternariol monomethyl ether, altenuene, and the degradation products was achieved by a newly developed high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) multimethod. The obtained quantitative data indicate that the Alternaria mycotoxins are barely degraded during wet baking, while significant degradation occurs upon dry baking, with the stability decreasing in the order alternariol monomethyl ether > alternariol > altenuene. The novel degradation products could be detected after the wet baking of flour spiked with alternariol and in a sample survey of 24 commercial cereal based baking products.
Affiliation
BAM Federal Institute for Materials Research and Testing, Richard-Willstatter-Strasse 11, 12489 Berlin, Germany.
Journal Details
This article was published in the following journal.
Name: Journal of agricultural and food chemistry
ISSN: 1520-5118
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20687560
- DOI: http://dx.doi.org/10.1021/jf102156w
Medical and Biotech [MESH] Definitions
Picolines
A group of compounds that are monomethyl derivatives of pyridines. (From Dorland, 28th ed)
Ether-a-go-go Potassium Channels
A family of voltage-gated potassium channels that are characterized by long N-terminal and C-terminal intracellular tails. They are named from the Drosophila protein whose mutation causes abnormal leg shaking under ether anesthesia. Their activation kinetics are dependent on extracellular MAGNESIUM and PROTON concentration.
Alternaria
A mitosporic Loculoascomycetes fungal genus including several plant pathogens and at least one species which produces a highly phytotoxic antibiotic. Its teleomorph is Lewia.
Mycotoxins
Toxic compounds produced by FUNGI.
Tenuazonic Acid
3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
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