Demography and Diffusion in Epidemics: Malaria and Black Death Spread.
Summary of "Demography and Diffusion in Epidemics: Malaria and Black Death Spread."
The classical models of epidemics dynamics by Ross and McKendrick have to be revisited in order to incorporate elements coming from the demography (fecundity, mortality and migration) both of host and vector populations and from the diffusion and mutation of infectious agents. The classical approach is indeed dealing with populations supposed to be constant during the epidemic wave, but the presently observed pandemics show duration of their spread during years imposing to take into account the host and vector population changes as well as the transient or permanent migration and diffusion of hosts (susceptible or infected), as well as vectors and infectious agents. Two examples are presented, one concerning the malaria in Mali and the other the plague at the middle-age.
Affiliation
LERTIM, EA 3283, Faculty of Medicine, Aix-Marseille University, 27 Bd Jean Moulin, 13385, Marseille Cedex 5, France, jean.gaudart@univmed.fr.
Journal Details
This article was published in the following journal.
Name: Acta biotheoretica
ISSN: 1572-8358
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20706773
- DOI: http://dx.doi.org/10.1007/s10441-010-9103-z
Medical and Biotech [MESH] Definitions
Pandemics
Epidemics of infectious disease that have spread to many countries, often more than one continent, and usually affecting a large number of people.
Malaria, Vivax
Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.
Blackwater Fever
A complication of MALARIA, FALCIPARUM characterized by the passage of dark red to black urine.
Diffusion Magnetic Resonance Imaging
A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.
Diffusion Tensor Imaging
The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.
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