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Esophageal resection for high-grade dysplasia and intramucosal carcinoma: When and how?

06:00 EDT 11th August 2010 | BioPortfolio

Summary of "Esophageal resection for high-grade dysplasia and intramucosal carcinoma: When and how?"

High-grade dysplasia (HGD) and intramucosal carcinoma (IMC) in the setting of Barrett's esophagus have traditionally been treated with esophagectomy. However, with the advent of endoscopic mucosal resection and endoscopic ablative therapies, endoscopic therapy at centers with expertise is now an established treatment of Barrett's-esophagus-related neoplasia, including HGD and IMC. Esophagectomy is today reserved for more selected cases with submucosal invasion, evidence for lymph node metastasis, or unsuccessful endoscopic therapy.

Affiliation

Department of Medicine, The University of Chicago Pritzker School of Medicine, 5841 S. Maryland Ave. MC 4076, Chicago, IL 60637, United States. vkonda@medicine.bsd.uchicago.edu.

Journal Details

This article was published in the following journal.

Name: World journal of gastroenterology : WJG
ISSN: 1007-9327
Pages: 3786-92

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