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Apraxia and Alzheimer's Disease: Review and Perspectives.

08:00 EDT 1st August 2013 | BioPortfolio

Summary of "Apraxia and Alzheimer's Disease: Review and Perspectives."

Apraxia is one of the cognitive deficits that characterizes Alzheimer's disease. Despite its prevalence and relevance to diagnosing Alzheimer's disease, this topic has received little attention and is without comprehensive review. The review herein is aimed to fill this gap by first presenting an overview of the impairment caused in different clinical situations: pantomime of tool use, single tool use, real tool use, mechanical problem solving, function and manipulation knowledge tasks, and symbolic/meaningless gestures. On the basis of these results, we then propose alternative interpretations regarding the nature of the underlying mechanisms impaired by the disease. Also presented are principal methodological issues precluding firm conclusions from being drawn.

Affiliation

Laboratoire d'Étude des Mécanismes Cognitifs (EA 3082), Institut de Psychologie, Université Lyon 2, 5, avenue Pierre Mendès-France, 69676, Bron Cedex, France, mathieu.lesourd@chu-lyon.fr.

Journal Details

This article was published in the following journal.

Name: Neuropsychology review
ISSN: 1573-6660
Pages:

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